1232815-54-1

Basic information

• Product Name: 2-methylsulfanyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine
• Synonyms: 2-methylsulfanyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine
• CAS NO: 1232815-54-1
• Molecular Weight: 241.316
• Mol File: 1232815-54-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-methylsulfanyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylsulfanyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine(1232815-54-1)
• EPA Substance Registry System: 2-methylsulfanyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine(1232815-54-1)

Safety Data

• Hazardous Substances Data: 1232815-54-1(Hazardous Substances Data)

Upstream product

• 1233094-95-5 7-bromo-2-methylsulfanyl-pyrrolo[2,1-f][1,2,4]triazine 
• 98-80-6 phenylboronic acid 
• 1232815-51-8 7-bromo-4-chloro-2-(methylsulfanyl)pyrrolo[2,1-f][1,2,4]triazine 
• 1232815-49-4 2-thioxo-2,3-dihydro-1H-pyrrolo[2,1-f][1,2,4]triazin-4-one 
• 1232815-48-3 1-(3-benzoyl-thioureido)-1H-pyrrole-2-carboxylic acid methyl ester 

Downstream Products

• 1232815-96-1 5-bromo-2-methylsulfanyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine 
• 1232815-55-2 2-methylsulfinyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine 
• 1232397-16-8 (7-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(3,4,5-trimethoxy-phenyl)amine 
• 1318629-63-8 7-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-ol 

Relevant articles and documents

Azabicyclo derivatives, preparation methods thereof, and pharmaceutical applications thereof

The invention relates to azabicyclo derivatives, preparation methods thereof, and pharmaceutical applications thereof. Specifically, the invention discloses compounds represented by a formula (I), or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs thereof. The invention also provides preparation methods of the derivatives, and applications of the derivatives in EGFR inhibitors. The definitions of the groups in the formula are defined in the specifications.

PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS

The present invention provides a compound of formula (I) or a salt form thereof, wherein Q1, Q2, Q3, and Q4 are as defined herein. The compound of formula (I) has ALK and/or JAK2 inhibitory activity, and may be used to treat proliferative disorders.