1245553-60-9

Basic information

• Product Name: N-(6-acetyl-2-bromo-3-methoxyphenyl)-2-(isopropylamino)-thiazole-4-carboxamide
• Synonyms: N-(6-acetyl-2-bromo-3-methoxyphenyl)-2-(isopropylamino)-thiazole-4-carboxamide
• CAS NO: 1245553-60-9
• Molecular Weight: 412.307
• Mol File: 1245553-60-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(6-acetyl-2-bromo-3-methoxyphenyl)-2-(isopropylamino)-thiazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(6-acetyl-2-bromo-3-methoxyphenyl)-2-(isopropylamino)-thiazole-4-carboxamide(1245553-60-9)
• EPA Substance Registry System: N-(6-acetyl-2-bromo-3-methoxyphenyl)-2-(isopropylamino)-thiazole-4-carboxamide(1245553-60-9)

Safety Data

• Hazardous Substances Data: 1245553-60-9(Hazardous Substances Data)

Upstream product

• 300831-03-2 2-(isopropylamino)thiazole-4-carboxylic acid hydrobromide salt 
• 923289-30-9 1-(2-amino-3-bromo-4-methoxyphenyl)ethanone 

Downstream Products

• 1421637-87-7 4-(8-bromo-7-methoxy-4-(phenylsulfonyl)quinolin-2-yl)-N-isopropylthiazol-2-amine 

Relevant articles and documents

A highly convergent and efficient synthesis of a macrocyclic hepatitis C virus protease inhibitor BI 201302

A highly convergent large scale synthesis of a 15-membered macrocyclic hepatitis C virus (HCV) protease inhibitor BI 201302 was achieved, in which the key features are the practical macrocyclization by Ru-catalyzed ring-closing metathesis (0.1 mol % Grela catalyst, 0.1-0.2 M concentration) and the efficient sulfone-mediated SNAr reaction.