1252007-76-3

Basic information

• Product Name: C₂₉H₃₄N₂O₈
• Synonyms: C₂₉H₃₄N₂O₈
• CAS NO: 1252007-76-3
• Molecular Weight: 538.598
• Mol File: 1252007-76-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₉H₃₄N₂O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₃₄N₂O₈(1252007-76-3)
• EPA Substance Registry System: C₂₉H₃₄N₂O₈(1252007-76-3)

Safety Data

• Hazardous Substances Data: 1252007-76-3(Hazardous Substances Data)

Upstream product

• 518-28-5 podofilox 
• 6559-91-7 4'-demethylepipodophyllotoxin 
• 290371-79-8 (5S,5aR,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxole-5-carbonitrile 
• 27578-60-5 1-(2-aminoethyl)piperidine 
• 278618-79-4 (5S,5aS,8aR,9R)-9-(4-Hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxole-5-carboxylic acid 

Relevant articles and documents

Design and synthesis of novel cytotoxic podophyllotoxin derivatives

In order to investigate the effect of different C4 linkage moieties on the cytotoxicity of podophyllotoxin derivatives, novel 4-N- and 4-C-substituted 4'-O-demethylepipodophyllotoxin derivatives were designed and synthesized. All the compounds were tested against A549 and MCF-7 tumor cells in vitro, and six compounds showed significant cytotoxicity. The most active compound 9f was superior to GL-331, and exhibited potent cytotoxicity with IC50 value at 10-7mol/L level.