1253404-34-0Relevant articles and documents
Novel Prolinamide Organocatalysts Based on Calix[4]arene Scaffold for the Enantioselective Direct Aldol Reaction
Li, Zheng-Yi,Lu, Cheng-Xi,Huang, Guoli,Ma, Jie-Jie,Sun, Hongsheng,Wang, Leyong,Pan, Yi
, p. 461 - 466 (2011/09/14)
A series of novel prolinamide organocatalysts based on calix[4]arene scaffold have been developed to catalyze the direct asymmetric aldol reaction of aromatic aldehydes and cyclohexanone. Under the optimal condition, high isolated yields (up to 99%) and enantioselectivities (up to 97% ee), and moderate diastereoselectivities (up to 85/15) were obtained.