7244-78-2

Basic information

• Product Name: 4-N-BUTOXYNITROBENZENE
• Synonyms: 4-N-BUTOXYNITROBENZENE 99+%;Butyl 4-Nitrophenyl Ether;1-Nitro-4-butoxybenzene;4-Butoxy-1-nitrobenzene;4-Butoxynitrobenzene;1-BUTOXY-4-NITROBENZENE;1-N-BUTOXY-4-NITROBENZENE;4-N-BUTOXYNITROBENZENE
• CAS NO: 7244-78-2
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.22
• Mol File: 7244-78-2.mol
• Article Data: 29

Chemical Properties

• Melting Point: 31 °C
• Boiling Point: 331.88°C (rough estimate)
• Flash Point: 31 °C
• Appearance: /
• Density: 1.1926 (rough estimate)
• Vapor Pressure: 0.00127mmHg at 25°C
• Refractive Index: 1.5150 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 4-N-BUTOXYNITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-BUTOXYNITROBENZENE(7244-78-2)
• EPA Substance Registry System: 4-N-BUTOXYNITROBENZENE(7244-78-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 7244-78-2(Hazardous Substances Data)

Usage

General Description

4-N-Butoxynitrobenzene is a chemical compound with the molecular formula C10H13NO3. It is a yellow crystalline solid that is commonly used in organic synthesis and as a precursor for various industrial chemicals. The butoxy group, consisting of four carbon atoms, is attached to the nitrobenzene ring, giving the compound its distinctive structure. 4-N-Butoxynitrobenzene is used in the production of dyes, pesticides, and pharmaceuticals, and it may also be utilized as an intermediate in the manufacturing of other organic compounds. Due to its chemical properties and versatility, 4-N-butoxynitrobenzene is an important ingredient in various industrial processes.

InChI:InChI=1/C10H13NO3/c1-2-3-8-14-10-6-4-9(5-7-10)11(12)13/h4-7H,2-3,8H2,1H3

Upstream product

• 109-65-9 1-bromo-butane 
• 824-78-2 4-nitrophenol sodium salt 
• 100-02-7 4-nitro-phenol 
• 54519-10-7 (allyl)(n-C₄H₉)3NBr 
• 350-46-9 4-Fluoronitrobenzene 
• 1643-19-2 tetrabutylammomium bromide 
• 71-36-3 butan-1-ol 
• 586-78-7 para-nitrophenyl bromide 
• 636-98-6 p-nitrobenzene iodide 
• 109-69-3 n-Butyl chloride 
• 100-00-5 4-chlorobenzonitrile 
• 1124-31-8 potassium 4-nitrophenolate 
• 542-69-8 1-iodo-butane 

Downstream Products

• 100-02-7 4-nitro-phenol 
• 1377324-61-2 C₃₂H₃₈N₄O₅ 
• 14921-52-9 <4-Heptoxybenzal>-4-butoxy-anilin 
• 1358788-65-4 C₁₅H₂₂N₂O₃ 
• 1358788-66-5 C₂₀H₃₀N₂O₅ 
• 183323-92-4 N(CH₃)4⁽¹⁺⁾*AuCl₃(O₂NC₆H₃OC₄H₉)^(1-) = [N(CH₃)4][AuCl₃(O₂NC₆H₃OC₄H₉)] 
• 183323-93-5 [AuCl₂(P(C₆H₅)3)(O₂NC₆H₃OC₄H₉)] 
• 183323-94-6 [AuCl(C₆H₃(NO₂)OC₄H₉)(C₆H₄NNC₆H₅)] 
• 183323-90-2 Hg(C₆H₃(NO₂)OC₄H₉)2 
• 1253404-34-0 C₁₅H₂₂N₂O₂ 
• 183323-89-9 ClHgC₆H₃(NO₂)OC₄H₉ 
• 49798-74-5 4-Butoxy-3-propoxymethyl-phenylamine 
• 49798-73-4 1-Butoxy-4-nitro-2-propoxymethyl-benzene 
• 49797-24-2 1-Butoxy-2-iodomethyl-4-nitro-benzene 

Relevant articles and documents

Ultrasound assisted the preparation of 1-butoxy-4-nitrobenzene under a new multi-site phase-transfer catalyst - Kinetic study

In the present research work deals with the preparation of 1-butoxy-4-nitrobenzene was successfully carried out by 4-nitrophenol with n-butyl bromide using aqueous potassium carbonate and catalyzed by a new multi-site phase-transfer catalyst (MPTC) viz.,

Synthesis and antimicrobial studies of new antibacterial azo-compounds active against staphylococcus aureus and listeria monocytogenes

Some novel (phenyl-diazenyl)phenols (4a–m) were designed and synthesized to be evaluated for their antibacterial activity. Starting from an active previously-synthesized azobenzene chosen as lead compound, we introduced some modifications and optimization of the structure, in order to improve solubility and drug conveyance. Structures of all newly-synthesized compounds were confirmed by 1H nuclear magnetic resonance (NMR), mass spectrometry, and UV-Vis spectroscopy. Antibacterial activity of the new compounds was tested with the dilution method against the bacteria strains Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa PAO1. All the compounds were selectively active against Gram-positive bacteria. In particular, compounds 4d, 4h, and 4i showed the highest activity against S. aureus and Listeria monocytogenes, reaching remarkable MIC100 values of 4 μg/mL and 8 μg/mL. The relationship between antimicrobial activity and compound structure has suggested that the presence of hydroxyl groups seems to be essential for antimicrobial activity of phenolic compounds.

Alkoxylation of 4-chloronitrobenzene with aliphatic alcohols and glycols in the presence of NaOH

The reaction of 4-chloronitrobenzene with aliphatic C1-n-C 4 alcohols and with mono-, di-, and triethylene glycols in the presence of NaOH in liquid ammonia at 15-50°C was studied.