1255709-84-2Relevant articles and documents
Formal [3+2]-cycloaddition-based approach using ethoxymethylene malonate derivatives: Novel and expedient access to functionalized N -acyliminium precursors
Saber, Moussa,Comesse, Sébastien,Dalla, Vincent,Da?ch, Adam,Sanselme, Morgane,Netchita?lo, Pierre
experimental part, p. 2197 - 2201 (2010/10/21)
Combination of a base, ethoxymethylene malonates, and α- bromoacetamides was used to reach structurally diverse α-alkoxy γ- lactams via a direct aza-MIRC sequence in excellent yields. Subsequent acidic treatment allowed the formed pyrrolo [2,1-a]isoquinoline alkaloid core to be isolated in high yield.
