1256151-61-7

Basic information

• Product Name: methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1-2)-6-O-tert-butyldiphenylsilyl-3,4-O-isopropylidene-β-D-galactopyranoside
• Synonyms: methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1-2)-6-O-tert-butyldiphenylsilyl-3,4-O-isopropylidene-β-D-galactopyranoside
• CAS NO: 1256151-61-7
• Molecular Weight: 744.909
• Mol File: 1256151-61-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1-2)-6-O-tert-butyldiphenylsilyl-3,4-O-isopropylidene-β-D-galactopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1-2)-6-O-tert-butyldiphenylsilyl-3,4-O-isopropylidene-β-D-galactopyranoside(1256151-61-7)
• EPA Substance Registry System: methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1-2)-6-O-tert-butyldiphenylsilyl-3,4-O-isopropylidene-β-D-galactopyranoside(1256151-61-7)

Safety Data

• Hazardous Substances Data: 1256151-61-7(Hazardous Substances Data)

Upstream product

• 125520-01-6 ethyl 2,3,4-tri-O-acetyl-1-thio-α-L-rhamnopyranoside 
• 114244-04-1 methyl 6-O-(tert-butyldiphenylsilyl)-3,4-O-isopropylidene-β-D-galactopyranoside 

Relevant articles and documents

Synthesis of a core disaccharide from the Streptococcus pneumoniae type 23F capsular polysaccharide antigen

The synthesis of methyl α-l-rhamnopyranosyl-(1→2)-β-d- galactopyranoside and methyl α-l-rhamnopyranosyl-(1→2)-3-(glycer-2- yl-phosphate)-β-d-galactopyranoside disaccharides from the Streptococcus pneumoniae type 23F capsular polysaccharide is reported. A simple protecting group strategy was followed using commercially available monosaccharides and phosphorylating reagents. H-Phosphonate and phosphoramidite coupling chemistries were explored for introducing the phosphodiester. Hydrazine hydrate was found to be a mild and efficient deacetylating agent, which was required to avoid phosphate migration during the deprotection of the phosphodiester functionalized disaccharide.