125803-35-2

Basic information

• Product Name: Benzeneacetonitrile, a-(acetyloxy)-2-chloro-
• CAS NO: 125803-35-2
• Molecular Formula: C10H8ClNO2
• Molecular Weight: 209.632
• Mol File: 125803-35-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetonitrile, a-(acetyloxy)-2-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetonitrile, a-(acetyloxy)-2-chloro-(125803-35-2)
• EPA Substance Registry System: Benzeneacetonitrile, a-(acetyloxy)-2-chloro-(125803-35-2)

Safety Data

• Hazardous Substances Data: 125803-35-2(Hazardous Substances Data)

Upstream product

• 66985-47-5 2-chloro-α-[(trimethylsilyl)oxy]benzeneacetonitrile 
• 108-24-7 acetic anhydride 
• 13312-84-0 2-chloromandelonitrile 
• 89-98-5 2-chloro-benzaldehyde 
• 631-57-2 Acetyl cyanide 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 52923-20-3 (S)-2-(2-chlorophenyl)-2-hydroxyacetonitrile 

Relevant articles and documents

Supported Ionic Liquid-Like Phases (SILLPs) as Immobilised Catalysts for the Multistep and Multicatalytic Continuous Flow Synthesis of Chiral Cyanohydrins

Supported Ionic Liquid-Like Phases have been found to be efficient organocatalysts for the synthesis of cyanohydrin esters under solvent-free conditions by an “electrophile-nucleophile dual activation” based on hydrogen bond formation. The combination of

N-heterocyclic carbene catalyzed cyanation reaction of carbonyl compounds with ethyl cyanoformate and acetyl cyanide

N-heterocyclic carbene (NHC) has been employed as an efficient catalyst for cyanation reaction of carbonyl compounds. Under catalysis of 1 mol % NHCs, various aldehydes and 2,2,2-trifluoroacetophenone coupled with ethyl cyanoformate in THF to provide cyanohydrins ethyl carbonates in excellent yields. While in the presence of 10 mol % catalyst, different types of aldehydes and 2,2,2-trifluoroacetophenone reacted with acetyl cyanide in dichloroethane to give acylated cyanohydrins in moderate to high yields.