126-31-8 Usage
Chemical Properties
A white, crystalline powder; odorless;
slight salty taste followed by sweetish aftertaste.
Decomposes on exposure to light, solutions are
neutral to litmus. Soluble in water; very soluble
in methanol; slightly soluble in alcohol; practically
insoluble in
Uses
Radiopaque contrast medium.
Brand name
Abrodil;Myelotrast;Neo-sombraven;Sergozin;Skiodan sodium;Urombal.
World Health Organization (WHO)
Methiodal sodium, a radio-opaque medium, was formerly used for
the examination of the urinary tract. Its use was associated with muscle spasms
presumed to result from irritation of motor nerve roots in the spinal canal. This led
to its withdrawal in Sweden in 1975 when a safer alternative became available.
Preparations containing methiodal sodium were subsequently withdrawn
worldwide by the manufacturer.
General Description
Colorless crystals.
Air & Water Reactions
Water soluble.
Reactivity Profile
Sensitive to light.
Health Hazard
ACUTE/CHRONIC HAZARDS: Toxic.
Check Digit Verification of cas no
The CAS Registry Mumber 126-31-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 6 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 126-31:
(5*1)+(4*2)+(3*6)+(2*3)+(1*1)=38
38 % 10 = 8
So 126-31-8 is a valid CAS Registry Number.
InChI:InChI=1/CH3IO3S.Na/c2-1-6(3,4)5;/h1H2,(H,3,4,5);/q;+1/p-1
126-31-8Relevant articles and documents
Protocol for Stereoselective Construction of Highly Functionalized Dienyl Sulfonyl Fluoride Warheads
Zhang, Zai-Wei,Wang, Shi-Meng,Fang, Wan-Yin,Lekkala, Ravindar,Qin, Hua-Li
, p. 13721 - 13734 (2020/12/15)
A pyrrolidine-mediated Knoevenagel-type reaction for highly stereoselective construction of novel α-halo-1,3-dienylsulfonyl fluorides was achieved in up to 100% Z-selectivity and high yields at room temperature from condensation of the readily available aldehydes and halomethanesulfonyl fluorides. This protocol provided a class of unique α-halo-1,3-dienylsulfonyl fluorides with wide scope and excellent functional group compatibility. The α-halo-1,3-dienylsulfonyl fluorides were used as versatile building blocks in sulfur fluoride exchange click chemistry, Suzuki reaction, and Sonogashira reaction for the assembly of highly functionalized dienyl sulfonyl fluoride derivatives to be applied as covalent warheads for the discovery of new drugs.
α-Haloalkanesulfonyl Bromides in Organic Synthesis. 3. α-Alkylidene Ketones and 1,3-Oxathiole 3,3-Dioxides from Trimethylsilyl Enol Ethers
Block, Eric,Aslam, Mohammad,Iyer, Rajeshwari,Hutchinson, John
, p. 3664 - 3666 (2007/10/02)
α-Alkylidene ketones and 1,3-oxathiole 3,3-dioxides can be conveniently prepared by treatment of trimethylsilyl enol ethers with α-haloalkanesulfonyl bromides followed by an amine base such as 1,5-diazabicyclonon-5-ene (DBN).
