1265906-07-7

Basic information

• Product Name: methyl 3-(2-azidoethoxy)benzoate
• Synonyms: methyl 3-(2-azidoethoxy)benzoate
• CAS NO: 1265906-07-7
• Molecular Weight: 221.216
• Mol File: 1265906-07-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-(2-azidoethoxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(2-azidoethoxy)benzoate(1265906-07-7)
• EPA Substance Registry System: methyl 3-(2-azidoethoxy)benzoate(1265906-07-7)

Safety Data

• Hazardous Substances Data: 1265906-07-7(Hazardous Substances Data)

Upstream product

• 59516-96-0 1-Bromo-2-(3'-carbomethoxyphenoxy)ethane 

Downstream Products

• 1265906-16-8 C₁₉H₂₅N₃O₉ 
• 1265906-19-1 C₁₉H₂₅N₃O₉ 
• 1265906-22-6 C₁₈H₂₃N₃O₉ 
• 1265906-25-9 C₁₈H₂₃N₃O₉ 
• 1265906-10-2 C₂₇H₃₃N₃O₁₃ 
• 1265906-13-5 C₂₇H₃₃N₃O₁₃ 

Relevant articles and documents

Microwave-accelerated click chemistry: Expeditious synthesis of novel triazole-linked salicylic β-D-O-glycosides with PTP1B inhibitory activity

The incorporation of microwave irradiation with the prevalent "click chemistry" is currently of considerable synthetic interest. We describe here the introduction of such laboratorial shortcut into carbohydrate-based drug discovery, resulting in the rapid formation of a series of triazole-linked salicylic β-D-O-glycosides with biological activities. All "clicked" products were achieved in excellent yields (≈90%) within only a quarter. In addition, based on the structural characteristics of the afforded glycomimetics, their inhibitory activities were evaluated toward protein tyrosine phosphatases 1B (PTP1B) and a panel of homologous protein tyrosine phosphatases (PTPs). Docking simulation was also conducted to plausibly propose binding modes of this glycosyl salicylate series with the enzymatic target.