59516-96-0

Basic information

• Product Name: METHYL 3-(2-BROMOETHOXY)BENZENECARBOXYLATE
• Synonyms: METHYL 3-(2-BROMOETHOXY)BENZENECARBOXYLATE;RARECHEM AL BF 1113;Methyl 3-(2-bromoethoxy)benzoate;Methyl 3-(2-broMoethoxy)benzoate, 97+%
• CAS NO: 59516-96-0
• Molecular Formula: C₁₀H₁₁BrO₃
• Molecular Weight: 259.1
• Mol File: 59516-96-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 110/0.038mm
• Flash Point: 150.255 °C
• Appearance: /
• Density: 1.431 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: METHYL 3-(2-BROMOETHOXY)BENZENECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-(2-BROMOETHOXY)BENZENECARBOXYLATE(59516-96-0)
• EPA Substance Registry System: METHYL 3-(2-BROMOETHOXY)BENZENECARBOXYLATE(59516-96-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 59516-96-0(Hazardous Substances Data)

Usage

Uses

Methyl 3-(2-bromoethoxy)benzoate used in pharmaceutical research.

InChI:InChI=1/C10H11BrO3/c1-13-10(12)8-3-2-4-9(7-8)14-6-5-11/h2-4,7H,5-6H2,1H3

Upstream product

• 19438-10-9 methyl 3-hydroxybenzoate 
• 540-51-2 2-bromoethanol 
• 106-93-4 ethylene dibromide 

Downstream Products

• 225122-64-5 2-amino-4-[3-(methoxycarbonyl)-phenoxy]-butyronitrile 
• 225121-08-4 N-[3-(3-(methoxycarbonyl)-phenoxy)-1-cyanopropyl]-3-methyl-Nα-(2,2-diphenylacetyl)-L-phenylalaninamide 
• 1265906-10-2 C₂₇H₃₃N₃O₁₃ 
• 1265906-07-7 methyl 3-(2-azidoethoxy)benzoate 
• 1265906-13-5 C₂₇H₃₃N₃O₁₃ 
• 1265906-16-8 C₁₉H₂₅N₃O₉ 
• 1265906-19-1 C₁₉H₂₅N₃O₉ 
• 1265906-22-6 C₁₈H₂₃N₃O₉ 
• 1265906-25-9 C₁₈H₂₃N₃O₉ 
• 921602-60-0 methyl 3-cyclopropoxybenzoate 
• 61031-63-8 methyl 3-(vinyloxy)benzoate 
• 866268-74-8 2-butoxy-9-[2-(3-methoxycarbonylphenoxy)ethyl]adenine 
• 165801-78-5 3-[2-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-ethoxy]-benzoic acid methyl ester 
• 225122-62-3 methyl 3-(2-iodoethoxy)benzoate 

Relevant articles and documents

Opioid receptor agonists and application thereof

The invention discloses compounds and salts thereof that can be used as opioid receptor ligands, a preparation method of the compounds, compositions containing the compounds, and a use of the compounds as [mu] opioid receptor agonists; the compounds are used for treatment of [mu] opioid receptor-mediated related diseases, such as pains and pain-related disorders.

Microwave-accelerated click chemistry: Expeditious synthesis of novel triazole-linked salicylic β-D-O-glycosides with PTP1B inhibitory activity

The incorporation of microwave irradiation with the prevalent "click chemistry" is currently of considerable synthetic interest. We describe here the introduction of such laboratorial shortcut into carbohydrate-based drug discovery, resulting in the rapid formation of a series of triazole-linked salicylic β-D-O-glycosides with biological activities. All "clicked" products were achieved in excellent yields (≈90%) within only a quarter. In addition, based on the structural characteristics of the afforded glycomimetics, their inhibitory activities were evaluated toward protein tyrosine phosphatases 1B (PTP1B) and a panel of homologous protein tyrosine phosphatases (PTPs). Docking simulation was also conducted to plausibly propose binding modes of this glycosyl salicylate series with the enzymatic target.

6-Membered heterocyclic compound and use thereof

A compound represented by the general formula (I) or a salt thereof: [T represents oxygen atom and the like; V represents CH2 and the like; RO1 to RO4 represent hydrogen atom and the like; A represents a linear alkylene group or linear alkenylene group having 2 to 8 carbon atoms and the like; D represents carboxyl group and the like; X represents ethylene group, trimethylene group and the like; E represents —CH(OH)— group and the like; and W represent —U1—(RW1)(RW2)—U2—U3 group (U1 represents a single bond, an alkylene group having 1 to 4 carbon atoms and the like; RW1 and RW2 represent hydrogen atom and the like; U2 represents a single bond, an alkylene group having 1 to 4 carbon atoms and the like; and U3 represent an alkyl group having 1 to 8 carbon atoms and the like), or a residue of a carbon ring or heterocyclic compound], which can be utilized as an active ingredient of medicaments effective for prophylactic and/or therapeutic treatment of skeletal diseases such as osteoporosis and fracture, glaucoma, ulcerative colitis and the like.