1269425-66-2

Basic information

• Product Name: (R)-4-(tert-butyldimethylsilyloxy)-1-tosylpyrrolidin-2-one
• Synonyms: (R)-4-(tert-butyldimethylsilyloxy)-1-tosylpyrrolidin-2-one
• CAS NO: 1269425-66-2
• Molecular Weight: 369.557
• Mol File: 1269425-66-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-(tert-butyldimethylsilyloxy)-1-tosylpyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-(tert-butyldimethylsilyloxy)-1-tosylpyrrolidin-2-one(1269425-66-2)
• EPA Substance Registry System: (R)-4-(tert-butyldimethylsilyloxy)-1-tosylpyrrolidin-2-one(1269425-66-2)

Safety Data

• Hazardous Substances Data: 1269425-66-2(Hazardous Substances Data)

Upstream product

• 131653-51-5 (4R)-4-((tert-butyl(dimethyl)silyl)oxy)pyrrolidin-2-one 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1269425-73-1 (4R)-4-(tert-butyldimethylsilyloxy)-1-tosylpyrrolidin-2-ol 
• 1269425-85-5 (1S,5R,7R)-5-(tert-butyldimethylsilyloxy)-3-tosyl-8-oxa-3-azabicyclo[5.1.0]octane 
• 1269425-84-4 (1R,5R,7S)-5-(tert-butyldimethylsilyloxy)-3-tosyl-8-oxa-3-azabicyclo[5.1.0]octane 

Relevant articles and documents

Remote chiral induction in vinyl sulfonium salt-mediated ring expansion of hemiaminals into epoxide-fused azepines

The planet of the azepines: Epoxy-fused azepines have been synthesized in a highly selective reaction with hemiaminals and vinyl sulfonium salts. Stereochemistry is controlled by the substituent at the four- or five-position of the hemiaminal. The key step involves ring-opening of the hemiaminal, conjugate addition onto a vinyl sulfonium salt, and epoxidation of the aldehyde by the in situ formed sulfur ylide. Copyright