1271994-21-8

Basic information

• Product Name: 1-(diphenylphosphinoylethynyl)isoquinoline
• Synonyms: 1-(diphenylphosphinoylethynyl)isoquinoline
• CAS NO: 1271994-21-8
• Molecular Weight: 353.36
• Mol File: 1271994-21-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(diphenylphosphinoylethynyl)isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(diphenylphosphinoylethynyl)isoquinoline(1271994-21-8)
• EPA Substance Registry System: 1-(diphenylphosphinoylethynyl)isoquinoline(1271994-21-8)

Safety Data

• Hazardous Substances Data: 1271994-21-8(Hazardous Substances Data)

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 86520-96-9 1-ethynylisoquinoline 
• 1271994-34-3 1-[(diphenylphosphanyl)ethynyl]isoquinoline 

Downstream Products

• 1271994-28-5 1-[6-(diphenylphosphanyl)-4,7-dimethyl-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-isoindol-5-yl]isoquinoline 

Relevant articles and documents

Enantioselective synthesis of axially chiral 1-arylisoquinolines by rhodium-catalyzed [2+2+2] cycloaddition

It's all in the application! An enantioselective synthesis of axially chiral 1-arylisoquinolines has been achieved, which involves a rhodium-catalyzed [2+2+2] cycloaddition of diphenylphosphinoyl-substituted 1-arylisoquinolines (see scheme). The new diphenylphosphinoyl-substituted axially chiral 1-arylisoquinolines were successfully derivatized to the corresponding axially chiral P,N ligand and Lewis base catalyst.