127931-48-0

Basic information

• Product Name: 1-(naphthalen-1-yl)-4-phenylbutane-1,4-dione
• Synonyms: 1-(naphthalen-1-yl)-4-phenylbutane-1,4-dione
• CAS NO: 127931-48-0
• Molecular Weight: 288.346
• Mol File: 127931-48-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(naphthalen-1-yl)-4-phenylbutane-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(naphthalen-1-yl)-4-phenylbutane-1,4-dione(127931-48-0)
• EPA Substance Registry System: 1-(naphthalen-1-yl)-4-phenylbutane-1,4-dione(127931-48-0)

Safety Data

• Hazardous Substances Data: 127931-48-0(Hazardous Substances Data)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 941-98-0 1'-naphthacetophenone 
• 364045-18-1 4-cyano-4-morpholino-4-phenyl-N-methoxy-N-methylbutyramide 
• 15190-10-0 morpholin-4-yl-phenyl-acetonitrile 
• 38858-73-0 1-phenyl-1-trimethylsiloxycyclopropane 
• 879-18-5 naphthalene-1-carbonic acid chloride 

Downstream Products

• 1014982-49-0 C₂₂H₁₇NO₂ 

Relevant articles and documents

Detrifluoroacetylation Reaction of Trifluoromethyl-β-diketones: Facile Method for the Synthesis of Succinimide Derivatives and 1,4-Diketones

Currently, a great deal of research efforts are focused on C–C bond activation for development of novel synthetic methodology. In this paper, a detrifluoroacetylation of trifluoromethyl-β-diketones is described, which allows for the synthesis of succinimides and 1,4-diketones through cascade Michael addition/retro-Claisen reaction and nucleophilic substitution/retro-Claisen reaction. The readily available trifluoromethyl-β-diketones, wide substrate scope, and mild conditions make this method very practical.

N-Methoxy-N-methyl-3-bromopropionamide: A new three carbon homologating agent for the synthesis of unsymmetrical 1,4-diketones

A synthetic route based on a three carbon homologation of an α-aminonitrile was developed for the synthesis of unsymmetrical 1,4-diketones. The key steps were the alkylation of various aryl and heteroaryl α-aminonitriles with N-methoxy-N-methyl-3-bromopropionamide followed by the addition of a Grignard reagent to the alkylated product and then subsequent hydrolysis.

Palladium- and platinum-catalyzed reaction of siloxycyclopropanes with acid chlorides. A homoenolate route to 1,4-dicarbonyl compounds

1,4-Keto esters and 1,4-diketones have been synthesized by the palladium-catalyzed reaction of siloxycylopropanes and acid chlorides.