1284218-99-0

Basic information

• Product Name: C₁₆H₁₃F₃O₂
• Synonyms: C₁₆H₁₃F₃O₂
• CAS NO: 1284218-99-0
• Molecular Weight: 294.273
• Mol File: 1284218-99-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₃F₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₃F₃O₂(1284218-99-0)
• EPA Substance Registry System: C₁₆H₁₃F₃O₂(1284218-99-0)

Safety Data

• Hazardous Substances Data: 1284218-99-0(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 104863-68-5 2-(benzyloxy)-N-methoxy-N-methylacetamide 
• 30379-55-6 benzyloxyacetic acid 

Downstream Products

• 1284219-11-9 C₁₇H₁₂F₆O₄S 
• 1284219-29-9 C₁₆H₁₁F₃O 

Relevant articles and documents

[3,3]-sigmatropic rearrangement/5-exo-dig cyclization reactions of benzyl alkynyl ethers: Synthesis of substituted 2-indanones and indenes

Substituted benzyl alkynyl ethers, prepared from the corresponding α-alkoxy ketones in a two-step sequence involving enol triflate formation and KOtBu-induced E2 elimination, undergo [3,3]-sigmatropic rearrangement/ intramolecular 5-exo-dig cyclization at 60 °C to form substituted 2-indanones in good overall yields. 1,3-cis-Disubstituted-2-indanones are formed preferentially when the benzylic substituent R1 is bulky. Substituted indenes may be prepared from 2-indanones in high yields by Horner-Wadsworth-Emmons reaction.