129149-57-1

Basic information

• Product Name: 1-Pyrrolidinecarboxaldehyde, 2-(1-hydroxy-1-methylethyl)-, (S)- (9CI)
• Synonyms: 1-Pyrrolidinecarboxaldehyde, 2-(1-hydroxy-1-methylethyl)-, (S)- (9CI)
• CAS NO: 129149-57-1
• Molecular Formula: C8H15NO2
• Molecular Weight: 157.2102
• Product Categories: ALDEHYDE
• Mol File: 129149-57-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Pyrrolidinecarboxaldehyde, 2-(1-hydroxy-1-methylethyl)-, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxaldehyde, 2-(1-hydroxy-1-methylethyl)-, (S)- (9CI)(129149-57-1)
• EPA Substance Registry System: 1-Pyrrolidinecarboxaldehyde, 2-(1-hydroxy-1-methylethyl)-, (S)- (9CI)(129149-57-1)

Safety Data

• Hazardous Substances Data: 129149-57-1(Hazardous Substances Data)

Upstream product

• 92053-25-3 (S)-(-)-2-(1-hydroxy-1-methylethyl)-pyrrolidine 
• 109-94-4 formic acid ethyl ester 
• 51207-68-2 (2S)-N-Benzyloxycarbony-2-(1'-hydroxy-1'-methylethyl)pyrrolidine 
• 5211-23-4 N-carbobenzyloxy-L-proline methyl ester 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 

Downstream Products

• 118971-00-9 (S)-(-)-2-(1-methoxy-1-methylethyl)-pyrrolidine 

Relevant articles and documents

A highly enantioselective synthesis of phosphate triesters

A general methodology for the preparation of both enantiomers of a variety of trialkyl phosphates with enantiomeric excesses ranging from 87 to 92% is described. Bis(2,4-dichlorophenyl) phosphoramidates bearing a 2-substituted pyrrolidine moiety as the chiral auxiliary are prepared and examined for their stereoselectivity. Considerations based on both the absolute configuration of the product phosphates as well as the X-ray structural determination of one of the bis(2,4-dichlorophenyl) phosphoramidates suggest these substitutions occur with preponderant inversion of configuration at phosphorus.