1301669-35-1

Basic information

• Product Name: (S)-ethyl 2-((S)-(tert-butoxycarbonylamino)(p-tolyl)-methyl)-2-fluoro-3-oxobutanoate
• Synonyms: (S)-ethyl 2-((S)-(tert-butoxycarbonylamino)(p-tolyl)-methyl)-2-fluoro-3-oxobutanoate
• CAS NO: 1301669-35-1
• Molecular Weight: 367.418
• Mol File: 1301669-35-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-ethyl 2-((S)-(tert-butoxycarbonylamino)(p-tolyl)-methyl)-2-fluoro-3-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-ethyl 2-((S)-(tert-butoxycarbonylamino)(p-tolyl)-methyl)-2-fluoro-3-oxobutanoate(1301669-35-1)
• EPA Substance Registry System: (S)-ethyl 2-((S)-(tert-butoxycarbonylamino)(p-tolyl)-methyl)-2-fluoro-3-oxobutanoate(1301669-35-1)

Safety Data

• Hazardous Substances Data: 1301669-35-1(Hazardous Substances Data)

Upstream product

• 1522-41-4 ethyl-2-fluoroacetoacetate 
• 479423-39-7 4-methylbenzaldehyde N-(tert-butoxycarbonyl)imine 

Relevant articles and documents

Asymmetric mannich-type reactions of fluorinated ketoesters with binaphthyl-modified thiourea catalysts

The catalytic enantioselective Mannich-type reaction promoted by chiral binaphthyl-modified bifunctional organocatalysts is described. The treatment of α-fluoro-β-ketoesters with N-Boc imines under mild reaction conditions afforded the corresponding β-aminated α-fluoro-β- ketoesters with excellent enantioselectivities (up to 98% ee).