479423-39-7

Basic information

• Product Name: Carbamic acid, [(4-methylphenyl)methylene]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(4-methylphenyl)methylene]-, 1,1-dimethylethyl ester (9CI);(4-Methyl-BENZYLIDENE)-CARBAMIC ACID TERT-BUTYL ESTER;(E)-tert-Butyl 4-MethylbenzylidenecarbaMate
• CAS NO: 479423-39-7
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219.27958
• Product Categories: N-BOC
• Mol File: 479423-39-7.mol
• Article Data: 25

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Carbamic acid, [(4-methylphenyl)methylene]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(4-methylphenyl)methylene]-, 1,1-dimethylethyl ester (9CI)(479423-39-7)
• EPA Substance Registry System: Carbamic acid, [(4-methylphenyl)methylene]-, 1,1-dimethylethyl ester (9CI)(479423-39-7)

Safety Data

• Hazardous Substances Data: 479423-39-7(Hazardous Substances Data)

Usage

General Description

Carbamic acid, [(4-methylphenyl)methylene]-, 1,1-dimethylethyl ester (9CI) is a chemical compound that belongs to the class of carbamic acid derivatives. It is also known as tert-butyl N-(p-tolyl)carbamate and has the molecular formula C13H17NO2. Carbamic acid, [(4-methylphenyl)methylene]-, 1,1-dimethylethyl ester (9CI) is commonly used in organic synthesis and pharmaceutical research as a reagent and intermediate. It is a colorless liquid with a high boiling point, making it suitable for various chemical reactions. Additionally, this compound may have potential applications in the agricultural and pharmaceutical industries due to its structural properties and reactivity. However, it is important to handle and use this chemical with caution due to its potential hazards and toxicity.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 104-87-0 4-methyl-benzaldehyde 
• 4248-19-5 tert-butyl carbazate 
• 479423-27-3 tert-butyl (phenylsulfonyl(p-tolyl)methyl)carbamate 
• 365441-83-4 tert-butyl (p-tolyl(tosyl)methyl)carbamate 

Downstream Products

• 1309658-00-1 (2S,3R)-3-[N-(t-butoxycarbonyl)-2-methyl-3-(4-methylphenyl)aziridine-2-carbonyl]-oxazolidin-2-one 
• 1309658-17-0 (2R,3S)-3-[N-(t-butoxycarbonyl)-2-methyl-3-(4-methylphenyl)aziridine-2-carbonyl]-oxazolidin-2-one 
• 1374758-56-1 (R)-tert-butyl 2-oxo-1-p-tolylhexylcarbamate 
• 1374758-42-5 tert-butyl (1S,2S)-2-formyl-1-p-tolylhexylcarbamate 
• 1355078-56-6 2-tert-butoxycarbonylamino-2-p-tolylethyl pivalate 
• 1313759-73-7 C₁₈H₂₆N₂O₆ 
• 1192024-61-5 (S)-benzyl 2-((S)-(tert-butoxycarbonylamino)(p-tolyl)-methyl)-2-fluoro-3-oxobutanoate 
• 1301669-35-1 (S)-ethyl 2-((S)-(tert-butoxycarbonylamino)(p-tolyl)-methyl)-2-fluoro-3-oxobutanoate 
• 1269668-01-0 C₂₂H₂₈N₂O₅S 

Relevant articles and documents

γ-Selective Vinylogous Aza-Morita-Baylis-Hillman Reaction with N -Carbamoylimines

Vinylogous aza-Morita-Baylis-Hillman (aza-MBH) reactions of a vinylcyclopentenone with N -Boc imines provide the corresponding γ-adducts in high regioselectivity (10 examples). While the corresponding reactions with N -Ts imines give the α-adducts and γ-a

Enantioselective Construction of Sulfur-Containing Tetrasubstituted Stereocenters via Asymmetric Functionalizations of α-Sulfanyl Cyclic Ketones

Asymmetric functionalizations of α-sulfanyl cyclic ketones were realized via chiral phosphoric acid catalyzed enantioselective addition reactions with aldimines, azodicarboxylates and allenamides. A series of chiral organosulfur compounds possessing sulfur-containing tetrasubstituted stereocenters were accessed via these methods, with excellent regioselectivities and high stereoselectivities. (Figure presented.).

Two Distinct Ag(I)- And Au(I)-Catalyzed Olefinations between α-Diazo Esters and N-Boc-Derived Imines

Metal-catalyzed reactions between α-diazo esters and imines were well-known to yield aziridine derivatives exclusively. This work reports two new olefination reactions between N-Boc-derived (Boc = tert-Butyloxycarbonyl) imines and α-diazo esters with Ag(I) and Au(I) catalysts, respectively. Our mechanistic studies reveal that these new olefinations involve an initial attack of diazo esters on metal/imine complexes to form Mannich-addition intermediates, which subsequently afford α-aryl-β-aminoacrylates via a Roskamp reaction, or to form β-aryl-β-aminoacrylates via the formation of silver carbenes.