130721-60-7

Basic information

• Product Name: 2-Oxazolidinone, 4-ethylidene-3-[(4-methylphenyl)sulfonyl]-, (4Z)-
• CAS NO: 130721-60-7
• Molecular Formula: C12H13NO4S
• Molecular Weight: 267.306
• Mol File: 130721-60-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 4-ethylidene-3-[(4-methylphenyl)sulfonyl]-, (4Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 4-ethylidene-3-[(4-methylphenyl)sulfonyl]-, (4Z)-(130721-60-7)
• EPA Substance Registry System: 2-Oxazolidinone, 4-ethylidene-3-[(4-methylphenyl)sulfonyl]-, (4Z)-(130721-60-7)

Safety Data

• Hazardous Substances Data: 130721-60-7(Hazardous Substances Data)

Upstream product

• 4083-64-1 Tosyl isocyanate 
• 63132-71-8 but-2-yn-1-yl tosylcarbamate 

Downstream Products

• 130799-65-4 4-Methyl-N-[(1R,2S,4R,5S)-1-tricyclo[3.2.1.0^2,4]oct-3-yl-prop-(Z)-ylidene]-benzenesulfonamide 

Relevant articles and documents

Efficient 1,3-Oxazolidin-2-one Synthesis through Heterogeneous PdII-Catalyzed Intramolecular Hydroamination of Propargylic Carbamates

Herein, we present an operationally simple protocol for the cycloisomerization of propargylic carbamates in which a heterogeneous catalyst consisting of Pd species immobilized on amino-functionalized siliceous mesocellular foam (PdII-AmP-MCF) i

Scalable synthesis of oxazolones from propargylic alcohols through multistep palladium(II) catalysis: β-selective oxidative heck coupling of cyclic sulfonyl enamides and aryl boroxines

A whale of a scale: The title oxidative Heck coupling proceeded with unusual β selectivity to generate a variety of branched substituted oxazolones (see scheme; Ts=p-toluenesulfonyl). The three-step synthesis from readily available starting materials with a simple palladium catalyst and inexpensive reagents could be carried out in a single reaction vessel or scaled up for the preparation of large amounts of these amino acid precursors. Copyright

Convenient synthesis of 4-methylene-2-oxazolidinones and 4-methylenetetrahydro-1,3-oxazin-2-ones via transition-metal catalyzed intramolecular addition of nitrogen atom to actylenic triple bond

2-Propynyl tosylcarbamates 1 undergo cyclization smoothly by the catalysis of CuCl/Et3N or AgNCO/Et3N to furnish 4-methylene-2-oxazolidinones 2 in good yields. The similar cyclization of the N-acyl derivatives of 1 (PhCO, MeCO, EtOCO, etc.) is catalyzed effectively by AgNCO/t-BuOK. These reactions accommodate a variety of substituents at C1 and C3 of 2-propyn-1-ol and provide (Z)-2 as single stereoisomers. The scope of the cyclization of 3-butynyl carbamates is rather limited, and in general only N-tosyl derivatives of terminally unsubstituted 3-butyn-1-ols undergo cyclization to give 4-methylenetetrahydro-1,3-oxazin-2-ones in synthetically useful yields by the catalysis of AgNCO/Et3N or AgNCO/t-BuOK.