63132-71-8

Basic information

• Product Name: Carbamic acid, [(4-methylphenyl)sulfonyl]-, 2-butynyl ester
• Synonyms: but-2-yn-1-yl tosylcarbamate;2-butynyl tosylcarbamate;Carbamic acid,[(4-methylphenyl)sulfonyl]-,2-butynyl ester
• CAS NO: 63132-71-8
• Molecular Formula: C12H13NO4S
• Molecular Weight: 267.306
• Mol File: 63132-71-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(4-methylphenyl)sulfonyl]-, 2-butynyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(4-methylphenyl)sulfonyl]-, 2-butynyl ester(63132-71-8)
• EPA Substance Registry System: Carbamic acid, [(4-methylphenyl)sulfonyl]-, 2-butynyl ester(63132-71-8)

Safety Data

• Hazardous Substances Data: 63132-71-8(Hazardous Substances Data)

Upstream product

• 764-01-2 methyl propargyl alcohol 
• 4083-64-1 Tosyl isocyanate 

Downstream Products

• 130721-60-7 (E)-4-ethylidene-3-tosyloxazolidin-2-one 
• 130721-60-7 (Z)-4-ethylidene-3-tosyloxazolidin-2-one 
• 70-55-3 toluene-4-sulfonamide 
• 929563-05-3 C₁₂H₁₃NO₄S 
• 130799-64-3 4-Eth-(Z)-ylidene-3-(toluene-4-sulfonyl)-oxazolidin-2-one 

Relevant articles and documents

Copper(II)-Catalyzed Aminohalogenation of Alkynyl Carbamates

A useful aminohalogenation reaction for the cyclization of O-alkynyl carbamates under copper catalysis has been developed. N-Halosuccinimides have been used as a halogen source. The intramolecular C?N bond formation occurs selectively affording haloalkyli

Palladium-catalyzed intramolecular hydroamination of propargylic carbamates and carbamothioates

An efficient and simple methodology was developed for the synthesis of oxazolidinones, oxazolidinthiones, imidazolidinthiones, and imidazolidinones from the corresponding propargylic starting materials using Pd(OAc)2 and n-Bu4NOAc as catalysts in DCE at room temperature.

Convenient synthesis of 4-methylene-2-oxazolidinones and 4-methylenetetrahydro-1,3-oxazin-2-ones via transition-metal catalyzed intramolecular addition of nitrogen atom to actylenic triple bond

2-Propynyl tosylcarbamates 1 undergo cyclization smoothly by the catalysis of CuCl/Et3N or AgNCO/Et3N to furnish 4-methylene-2-oxazolidinones 2 in good yields. The similar cyclization of the N-acyl derivatives of 1 (PhCO, MeCO, EtOCO, etc.) is catalyzed effectively by AgNCO/t-BuOK. These reactions accommodate a variety of substituents at C1 and C3 of 2-propyn-1-ol and provide (Z)-2 as single stereoisomers. The scope of the cyclization of 3-butynyl carbamates is rather limited, and in general only N-tosyl derivatives of terminally unsubstituted 3-butyn-1-ols undergo cyclization to give 4-methylenetetrahydro-1,3-oxazin-2-ones in synthetically useful yields by the catalysis of AgNCO/Et3N or AgNCO/t-BuOK.