1309440-27-4Relevant articles and documents
Diastereoselectively switchable enantioselective trapping of carbamate ammonium ylides with imines
Jiang, Jun,Xu, Hua-Dong,Xi, Jian-Bei,Ren, Bai-Yan,Lv, Feng-Ping,Guo, Xin,Jiang, Li-Qin,Zhang, Zhi-Yong,Hu, Wen-Hao
supporting information; experimental part, p. 8428 - 8431 (2011/07/29)
The diastereoselectively switchable enantioselective trapping of protic carbamate ammonium ylides with imines is reported. The intriguing Rh 2(OAc)4 and chiral Bronsted acid cocatalyzed three-component Mannich-type reaction of a diazo compound, a carbamate, and an imine provides rapid and efficient access to both syn- and anti-α- substituted α,β-diamino acid derivatives with a high level control of chemo-, diastereo-, and enantioselectivity.