1312815-01-2Relevant articles and documents
Novel ATP competitive MK2 inhibitors with potent biochemical and cell-based activity throughout the series
Oubrie, Arthur,Kaptein, Allard,De Zwart, Edwin,Hoogenboom, Niels,Goorden, Rianne,Van De Kar, Bas,Van Hoek, Maaike,De Kimpe, Vera,Van Der Heijden, Ruud,Borsboom, Judith,Kazemier, Bert,De Roos, Jeroen,Scheffers, Michiel,Lommerse, Jos,Schultz-Fademrecht, Carsten,Barf, Tjeerd
, p. 613 - 618 (2012)
Optimization of our previously described pyrrolopiperidone series led to the identification of a new benzamide sub-series, which exhibits consistently high potency in biochemical and cell-based assays throughout the series. Strong inhibition of LPS-induce
MK2 INHIBITORS
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Page/Page column 48-49, (2011/07/07)
The present invention relates to compounds of general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used in the treatment of immune, autoimmune, inflammatory diseases, cardiovascular diseases, infectious diseases, bone re
