13228-41-6Relevant articles and documents
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Stephens,Castro
, p. 3313 (1963)
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Improved synthesis of indoles from 2,3-epoxypropionic acid esters [5]
Shchelkunov,Yashnova,Li,Shchelkunov
, p. 1319 - 1319 (2002)
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A Synthetic Route to Chiral Benzo-Fused N-Heterocycles via Sequential Intramolecular Hydroamination and Asymmetric Hydrogenation of Anilino-Alkynes
Xu, Cong,Feng, Yu,Li, Faju,Han, Jiahong,He, Yan-Mei,Fan, Qing-Hua
, p. 3979 - 3990 (2019/11/14)
An efficient sequential intramolecular hydroamination/asymmetric hydrogenation reaction under catalysis of a single chiral ruthenium complex or a binary system consisting of achiral gold complex and chiral ruthenium complex has been reported. A diverse range of enantioenriched benzo-fused N-heterocycles, including 1,2,3,4-tetrahydroquinoline, indoline, and 2,3,4,5-tetrahydro-1H-benzo[b]azepine derivatives, were obtained from anilino-alkynes in high yields (up to 98%) with moderate to excellent enantioselectivities (up to 98% ee) under mild conditions. This protocol features good functional group tolerance and high atom economy. Furthermore, this catalytic protocol is applicable to gram-scale synthesis of a naturally occurring alkaloid, (-)-Angustureine.
Asymmetric Assisted Tandem Catalysis: Hydroamination followed by Asymmetric Friedel–Crafts Reaction from a Single Chiral N,N,N′,N′-Tetradentate Pyridylmethylamine-Based Ligand
Aillerie, Alexandre,Rodriguez-Ruiz, Violeta,Carlino, Romain,Bourdreux, Flavien,Guillot, Régis,Bezzenine-Lafollée, Sophie,Gil, Richard,Prim, Damien,Hannedouche, Jér?me
, p. 2455 - 2460 (2016/08/25)
With the rising interest in asymmetric catalysis promoted by earth-abundant elements, a chiral ligand will undoubtedly be the most valuable unit of the catalyst. The first proof of concept of the use of a multitask chiral ligand in an asymmetric assisted