13269-19-7

Basic information

• Product Name: 2-Nitro-3-pyridinamine
• Synonyms: 2-nitryl-3-aminopyridine;3-Pyridinamine, 2-nitro-;2-nitro-3-pyridinamine;3-Pyridinamine,2-nitro-(9CI);3-amino-2-nitripyridine;3-AMINO-2-NAPHTHOL;2-Nitrio-3-pyridineamine;2-Nitro-3-pyridinami
• CAS NO: 13269-19-7
• Molecular Formula: C₅H₅N₃O₂
• Molecular Weight: 139.11
• EINECS: 236-260-9
• Product Categories: NITRO;Amines;Pyridines;Pyridine;Heterocyclic Compounds;CHIRAL CHEMICALS;Building Blocks;C5;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis;Heterocycle-Pyridine series
• Mol File: 13269-19-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 194 °C
• Boiling Point: 382.3 °C at 760 mmHg
• Flash Point: 185℃
• Appearance: light yellow cryst
• Density: 1.437
• Vapor Pressure: 4.77E-06mmHg at 25°C
• Refractive Index: 1.645
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -1.66±0.22(Predicted)
• BRN: 124467
• CAS DataBase Reference: 2-Nitro-3-pyridinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Nitro-3-pyridinamine(13269-19-7)
• EPA Substance Registry System: 2-Nitro-3-pyridinamine(13269-19-7)

Safety Data

• Hazard Codes: Xn
• Statements: 23/24/25-36/37/38-20/21/22-22
• Safety Statements: 28-36/37/39-45-36-26-24/25
• PackingGroup: II
• Hazardous Substances Data: 13269-19-7(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow Cryst

InChI:InChI=1/C5H5N3O2/c6-4-2-1-3-7-5(4)8(9)10/h1-3H,6H2

Upstream product

• 74037-50-6 3-ethoxy-2-nitropyridine 
• 15862-54-1 β-N-nitraminopyridine 
• 28664-54-2 2-nitro-3-azidopyridine 
• 74-89-5 methylamine 
• 55304-91-1 ethyl N-(2-nitro-3-pyridyl)carbamate 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 95-54-5 1,2-diamino-benzene 
• 85676-60-4 N-(2-nitro-3-pyridyl)-N-phenacylmethanesulphonamide 
• 462-08-8 pyridin-3-ylamine 
• 6276-11-5 3-ethoxycarbonylaminopyridine 
• 123494-96-2 N-<3-(2-nitro-pyridyl)>succinimide 
• 151-50-8 potassium cyanide 
• 10486-08-5 sodium p-thiocresolate 
• 141-52-6 sodium ethanolate 

Downstream Products

• 1305317-30-9 3-amino-4-bromo-2-nitropyridine 
• 1232431-75-2 2,3-diamino-4-bromopyridine 
• 1305317-31-0 8-bromo-2,3-diphenylpyrido[2,3-b]pyrazine 
• 1305317-32-1 8-bromo-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-33-2 8-azido-2,3-diphenylpyrido[2,3-b]pyrazine 
• 1305317-34-3 8-azido-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-35-4 8-amino-2,3-diphenylpyrido[2,3-b]pyrazine 
• 1305317-36-5 8-amino-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-37-6 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-ethylurea 
• 1305317-38-7 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-phenylurea 
• 1305317-39-8 N-(3-chlorophenyl)-N'-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)urea 
• 1305317-40-1 N-[2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazin-8-yl]-N'-ethylurea 
• 1305317-41-2 N-[2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazin-8-yl]-N'-phenylurea 
• 1305317-42-3 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-ethylthiourea 

Relevant articles and documents

DIPYRIDOIMIDAZOLDERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS

This invention relates to a series of substituted 3-oxo-pyrrolo[1,2-a]imidazopyridine derivatives of the formula 1 where X1-X4, R1, R2 and Ar are defined herein. In addition the invention relates to pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are ligands for the benzodiazepine site on the GABA-A receptor and display anxiolytic and anticonvulsant activity in animal models.

3-(2-Imidazo[4,5-b]pyridine)propionic acid and some of its derivatives with suspected tuberculostatic activity

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SYNTHESES WITH AROMATIC NITRAMINES, V. PHOTOCHEMICAL REARRANGEMENT OF NITRAMINOPYRIDINES

All three isomeric nitraminopyridines were photolysed in methanol with low-pressure mercury lamp (253.7 nm). 2-Nitraminopyridine yielded both 2-amino-3-nitro- and 2-amino-5-nitropyridines (isomer ratio 6.26 : 1). 3-Nitropyridine rearranged into both 4-nitro- and 2-nitro-3-aminopyridines (isomer ratio 1.28 : 1), whereas 4-nitraminopyridine gave 3-nitro-4-aminopyridine as the sole product. 1-Methyl-2-nitriminopyridine did not rearrange under the conditions applied, but 1-methyl-4-nitriminopyridine gave 3-nitro-4-methylaminopyridine.The latest product was also obtained when the same starting material was rearranged in conc. sulfuric acid.