133039-10-8

Basic information

• Product Name: 2,4,6-trimethyl-1-(3-phenyl-2-propen-1-yl)benzene
• Synonyms: 2,4,6-trimethyl-1-(3-phenyl-2-propen-1-yl)benzene
• CAS NO: 133039-10-8
• Molecular Weight: 236.357
• Mol File: 133039-10-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2,4,6-trimethyl-1-(3-phenyl-2-propen-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-trimethyl-1-(3-phenyl-2-propen-1-yl)benzene(133039-10-8)
• EPA Substance Registry System: 2,4,6-trimethyl-1-(3-phenyl-2-propen-1-yl)benzene(133039-10-8)

Safety Data

• Hazardous Substances Data: 133039-10-8(Hazardous Substances Data)

Upstream product

• 64545-28-4 1-phenyl-3-(2,4,6-trimethylphenyl)prop-2-en-1-one 
• 487-68-3 mesytaldehyde 
• 98-86-2 acetophenone 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 108-67-8 1,3,5-trimethyl-benzene 
• 2327-99-3 1-phenylpropadiene 
• 29000-10-0 (E)-cinnamyl(triphenyl)stannane 
• 37464-41-8 phenyl 3-phenyl-allyl ether 
• 5980-97-2 mesitylboronic acid 
• 38276-72-1 1-methoxy-4-[[(2E)-3-phenyl-2-propen-1-yl]oxy]benzene 
• 2633-66-1 2-mesitylmagnesium bromide 
• 1333226-20-2 C₂₃H₂₃NO₄S₂ 

Relevant articles and documents

Cross-coupling reaction of allylic ethers with aryl Grignard reagents catalyzed by a nickel pincer complex

A cross-coupling reaction of allylic aryl ethers with arylmagnesium reagents was investigated using β-aminoketonato- and β-diketiminato-based pincer-type nickel(II) complexes as catalysts. An β-aminoketonato nickel(II) complex bearing a diphenylphosphino group as a third donor effectively catalyzed the reaction to afford the target cross-coupled products, allylbenzene derivatives, in high yield. The regioselective reaction of a variety of substituted cinnamyl ethers proceeded to give the corresponding linear products. In contrast, α- and γ-alkyl substituted allylic ethers afforded a mixture of the linear and branched products. These results indicated that the coupling reaction proceeded via a π-allyl nickel intermediate.

Palladium-catalyzed allylic arylation of allylic ethers with arylboronic acids using hydrazone ligands

Unsymmetrical 1,3-diarylpropenes were synthesized in good to high yields by the palladium-catalyzed allylic arylation of allylic ethers, such as a cinnamyl phenyl ether, with a variety of arylboronic acids using a hydrazone 1a-Pd(OAc)2 system in DMAc/H2O. Using this catalyst, eugenol was also synthesized from allyl phenyl ether with (4-hydroxy-3- methoxyphenyl)boronic acid pinacol ester. A palladium-catalyzed allylic arylation of cinnamyl phenyl ether derivatives with a variety of arylboronic acids using 5 mol-% of a hydrazone 1a-Pd(OAc)2 system in DMAc/H 2O at 50 °C gave 1,3-diarylpropenes in good yields. We also succeeded with the synthesis of eugenol by a palladium-catalyzed allylic arylation. Copyright

Homogeneous silver(I) salts and heterogeneous Ag3PW 12O40-catalyzed intermolecular allylation of arenes with allylic alcohols

AgOTf is an effective catalyst for intermolecular allylation of aromatic and heteroaromatic compounds with allylic alcohols affording allylated arenes in up to 99% yields. Heterogeneous allylation of arenes catalyzed by Ag 3PW12O40 gave comparable product yields to those obtained by AgOTf. Ag3PW12O40 could be reused five times with slightly decreased activity. Georg Thieme Verlag Stuttgart · New York.