133772-18-6 Usage
General Description
2-Iodomethyl benzoic acid methyl ester is a chemical compound often used in the field of organic synthesis. It belongs to the ester chemical group, which is characterized by a carbonyl adjacent to an ether linkage. 2-Iodomethyl benzoic acid methyl ester consists of a methyl benzoic acid molecule substituted with an iodomethyl group. Its molecular formula is C9H9IO3. However, like all chemicals, it should be handled with care as it can pose risk if ingested or if it comes into contact with the skin or eyes. It is highly crucial to follow safety guidelines when using this substance, particularly in laboratory settings.
Check Digit Verification of cas no
The CAS Registry Mumber 133772-18-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,7,7 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 133772-18:
(8*1)+(7*3)+(6*3)+(5*7)+(4*7)+(3*2)+(2*1)+(1*8)=126
126 % 10 = 6
So 133772-18-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H9IO2/c1-12-9(11)8-5-3-2-4-7(8)6-10/h2-5H,6H2,1H3
133772-18-6Relevant articles and documents
Catalytic Halogen Bond Activation in the Benzylic C-H Bond Iodination with Iodohydantoins
Combe, Sascha H.,Hosseini, Abolfazl,Song, Lijuan,Hausmann, Heike,Schreiner, Peter R.
, p. 6156 - 6159 (2017)
This letter presents the side-chain iodination of electron-deficient benzylic hydrocarbons at rt using N-hydroxyphthalimide (NHPI) as radical initiator and 1,3-diiodo-5,5-dimethylhydantoin and 3-iodo-1,5,5-trimethylhydantoin (3-ITMH) as iodine source. Addition of a carboxylic acid increased the reactivity due to complex formation with and activation of 3-ITMH by proton transfer and halogen bond formation. No SEAr reactions were observed under the employed reaction conditions. Our method enables convenient product isolation and gives 50-72% yields of isolated products.
