13400-13-0

Basic information

• Product Name: Caesium fluoride
• Synonyms: Anti-CSF 140 kDa subunit;Anti-Kalinin/nicein/epiligrin 100 kDa subunit;Anti-Ladsin 140 kDa subunit;Anti-Laminin 5 gamma 2 subunit;Anti-Laminin B2t chain;Anti-Laminin subunit gamma-2;Cesium fluoride, 99% trace metals basis;Cesium fluoride (Cs2F2)
• CAS NO: 13400-13-0
• Molecular Formula: CsF
• Molecular Weight: 151.9
• EINECS: 236-487-3
• Product Categories: Pyrimidines;AlphabeticalBiochemicals and Reagents;Biochemicals and Reagents;Density Gradient;Salts of Alkali Metals;CesiumProtection and Derivatization;Crystal Grade Inorganics;Cesium SaltsProtection and Derivatization;Deprotecting Reagents;Fluoride Sources;CesiumMetal and Ceramic Science;Inorganic Salts;Salts;Synthetic Reagents;metal halide;Deprotecting Reagents;Fluoride Sources;Cesium;Cesium Salts;Chemical Synthesis;Inorganic Salts;Materials Science;Metal and Ceramic Science;Protection and Derivatization;Synthetic Reagents
• Mol File: 13400-13-0.mol

Chemical Properties

• Melting Point: 682 °C(lit.)
• Boiling Point: 1251 °C
• Flash Point: 1251°C
• Appearance: White/Powder/Lump
• Density: 4.115 g/mL at 25 °C(lit.)
• Vapor Pressure: 922mmHg at 25°C
• Storage Temp.: 0-6°C
• Solubility: H2O: 3 M at 20 °C, clear, colorless
• Water Solubility: 369 g/100 mL (18 ºC)
• Sensitive: Hygroscopic
• Stability: hygroscopic
• Merck: 14,2012
• CAS DataBase Reference: Caesium fluoride(CAS DataBase Reference)
• NIST Chemistry Reference: Caesium fluoride(13400-13-0)
• EPA Substance Registry System: Caesium fluoride(13400-13-0)

Safety Data

• Hazard Codes: T,C
• Statements: 23/24/25-34-62-41-38-32
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2923 8/PG 2
• WGK Germany: 3
• RTECS: FK9650000
• F: 3-10
• TSCA: T
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 13400-13-0(Hazardous Substances Data)

Usage

Description

Caesium fluoride can be used as an analytical reagent, and also for the manufacture of optical crystals It can be used for the preparation of fluorinated isocyanate. During the Suzuki cross-coupling synthesis reaction, it can be used as a base for the positive substitution of the biaryls compound; it can also be used as a nucleophile for the fluorination of protic mediate such as the halide and sulfonate contained in tert-butyl alcohol or t-amyl alocohol. It can also be used as catalyst for the Silyl enol ether reaction of carbonyl compounds; used for efficient synthesis of single crystal Dion-Jacobson phase CsLaTa2O7 tto be applied to photocatalytic and superconductivity.

Chemical Properties

white crystalline powder

Uses

Different sources of media describe the Uses of 13400-13-0 differently. You can refer to the following data:
1. Used as a base in a Suzuki cross-coupling synthesis of ortho-substituted biaryls.5 Also employed as a reagent for nucleophilic fluorination of primary halides and sulfonates in protic media such as tert-butyl and tert-pentyl alcohols.6
2. A preperation of building block for synthesis of fluoroallylic compounds.
3. Catalyst in oxidation reactions; as a solid base when adsorbed onto Celite, q.v. Fluoride source in organic synthesis. Inorganic scintillator.

General Description

Cesium fluoride is an inorganic compound known to be a source of fluoride ion and a catalyst in organic synthesis. It has been used in many organic reactions like 1,4?elimination, desilylation, transesterification, acylation, nucleophilic aromatic substitution, etherification, cross?coupling reactions and so on.

Hazard

A poison.

Flammability and Explosibility

Notclassified

Safety Profile

A poison. Incompatible with benzenediazonium tetrafluoroborate and difluoroamine. When heated to decomposition it emits toxic fumes of F-.

Purification Methods

Crystallise it from aqueous solution by adding ethanol.

InChI:InChI=1/Cs.FH/h;1H/q+1;/p-1