1351669-43-6Relevant articles and documents
Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the ras-signaling modulators palmostatin B and M
Rusch, Marion,Zimmermann, Tobias J.,Bürger, Marco,Dekker, Frank J.,G?rmer, Kristina,Triola, Gemma,Brockmeyer, Andreas,Janning, Petra,B?ttcher, Thomas,Sieber, Stephan A.,Vetter, Ingrid R.,Hedberg, Christian,Waldmann, Herbert
, p. 9838 - 9842 (2011/12/02)
Finding the target: Activity-based proteomic profiling probes based on the depalmitoylation inhibitors palmostatin B and M (see picture) have been synthesized and were found to target acyl protein thioesterase 1 (APT1) and 2 (APT2) in cells. Copyright