65423-25-8

Basic information

• Product Name: 11-DODECENOIC ACID
• Synonyms: 11-DODECENOIC ACID;11C-DODECENOIC ACID;DELTA 11 CIS DODECENOIC ACID;11-cis-Dodecenoic acid;dodec-11-enoic acid
• CAS NO: 65423-25-8
• Molecular Formula: C₁₂H₂₂O₂
• Molecular Weight: 198.3
• Product Categories: Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives
• Mol File: 65423-25-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 20°C
• Boiling Point: 321.28°C (estimate)
• Flash Point: 200.3°C
• Appearance: /
• Density: 0.9014
• Vapor Pressure: 0.000219mmHg at 25°C
• Refractive Index: 1.4510
• PKA: 4.78±0.10(Predicted)
• CAS DataBase Reference: 11-DODECENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 11-DODECENOIC ACID(65423-25-8)
• EPA Substance Registry System: 11-DODECENOIC ACID(65423-25-8)

Safety Data

• Hazardous Substances Data: 65423-25-8(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid; fatty, citrusy aroma.

InChI:InChI=1/C12H22O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2H,1,3-11H2,(H,13,14)

Upstream product

• 1647-16-1 1,10-decadiene 
• 108-24-7 acetic anhydride 
• 71736-19-1 12-iodododecan-1-oic acid 
• 7766-50-9 1-undecen-11-ylbromide 
• 124-38-9 carbon dioxide 

Downstream Products

• 123-99-9 azelaic acid 
• 610308-75-3 1,2-di-(11'-dodecenoyl)-3-(p-methoxybenzyl)-sn-glycerol 
• 17278-73-8 13-Hydroxymyristic acid 
• 1351669-61-8 (S)-methyl 2-((S)-3-(3,4-dimethoxyphenyl)-1-hydroxypropyl)dodec-11-ynoate 
• 1351669-43-6 (3S,4S)-3-(dec-9-ynyl)-4-(3,4-dimethoxyphenetyl)oxetan-2-one 
• 1351669-60-7 (S)-2-((S)-3-(3,4-dimethoxyphenyl)-1-hydroxypropyl)dodec-11-ynoic acid 
• 1351669-57-2 (S)-((1S,2R)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl) 2-((S)-1-5-(3-dimethylaminopropylsulfonyl)-1-hydroxypentyl)dodec-11-ynoate 
• 1351669-55-0 (S)-((1S,2R)-2-(N-benzyl-2,4,6-trimethylphenylsulfonamido)-1-phenylpropyl) 2-((S)-3-(3,4-dimethoxyphenyl)-1-hydroxypropyl)dodec-11-ynoate 
• 1310330-47-2 C₂₈H₄₄O₂Si 
• 16900-60-0 dodec-11-ynoic acid 
• 99824-64-3 dodec-11-en-1-yl 4-methylbenzenesulfonate 
• 1026563-20-1 (2-Dodec-11-enyl-2H-tetrazol-5-yl)-phenyl-acetic acid ethyl ester 
• 177431-83-3 (2-Dodec-11-enyl-2H-tetrazol-5-yl)-phenyl-acetic acid 
• 71084-07-6 1-tetrahydropyranyloxy 11-dodecyne 

Relevant articles and documents

A CONVENIENT AND EFFICIENT THREE-STEP SYTHESIS OF α-CHLORO KETO ACIDS

Efficient three-step syntheses of α-chloro keto acids 1a-c from ω-alkenoic acids 2 and ω-alkenyl alcohols 3 are described, proceeding via epoxidation/chloride-mediated epoxide ring opening/Jones oxidation protocols.

The Rickiols: 20-, 22-, and 24-membered Macrolides from the Ascomycete Hypoxylon rickii

In preceding studies the neotropical ascomycete Hypoxylon rickii turned out to be a prolific source of new secondary metabolites, considering that we had obtained terpenoids with five different scaffolds along with a series of terphenyls. From the mycelial extracts of a 70 L scale fermentation of this strain we additionally isolated nine new macrolides (1–9) by RP-HPLC. The planar structures were elucidated by NMR spectroscopy complemented by HR-ESIMS. The relative configurations were assigned by J-based configuration analyses and confirmed by Kishi′s Universal Database. Subsequently, the absolute configurations were assigned by Mosher′s method using the shift analysis of a tetra-MTPA derivative. For rickiol A (1) and E (5) we observed transesterification of 20-membered ring structures to 22-membered isomers rickiol A2 (6) and E2 (7), and to 24-membered isomers rickiol A3 (8) and rickiol E3 (9), respectively. Cytotoxic effects and moderate antibiotic activity against Gram-positive bacteria were observed for 1–8 and 1–6 and 8, respectively. The total synthesis of rickiol E3 (9) established easier access to these compounds.

A dehydrohalogenation methodology for synthesizing terminal olefins under mild conditions

A new methodology for preparing terminal olefins in good yield by dehydrohalogenation of primary alkyl iodide with tetrabutylammonium fluoride in dimethyl sulfoxide at room temperature is presented. Optimization of the mild reaction conditions and assays on various alkyl iodides are described. Georg Thieme Verlag Stuttgart.