1352144-38-7

Basic information

• Product Name: 7-chloro-4-[4-(1,1-difluoroethyl)phenyl]-6H-pyrrolo[1,2-a][1,4]-benzodiazepine
• Synonyms: 7-chloro-4-[4-(1,1-difluoroethyl)phenyl]-6H-pyrrolo[1,2-a][1,4]-benzodiazepine
• CAS NO: 1352144-38-7
• Molecular Weight: 356.802
• Mol File: 1352144-38-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-chloro-4-[4-(1,1-difluoroethyl)phenyl]-6H-pyrrolo[1,2-a][1,4]-benzodiazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-4-[4-(1,1-difluoroethyl)phenyl]-6H-pyrrolo[1,2-a][1,4]-benzodiazepine(1352144-38-7)
• EPA Substance Registry System: 7-chloro-4-[4-(1,1-difluoroethyl)phenyl]-6H-pyrrolo[1,2-a][1,4]-benzodiazepine(1352144-38-7)

Safety Data

• Hazardous Substances Data: 1352144-38-7(Hazardous Substances Data)

Upstream product

• 418762-90-0 2-(1H-pyrrol-1-yl)benzenemethanamine hydrochloride salt 
• 1352144-35-4 7-chloro-4-[4-(1,1-difluoroethyl)phenyl]-5,6-dihydro-4H-pyrrolo[1,2-a][1,4]-benzodiazepine hydrochloride 
• 418762-89-7 2-chloro-6-(1H-pyrrol-1-yl)benzonitrile 
• 1352144-70-7 C₂₀H₁₇ClF₂N₂O 

Relevant articles and documents

NOVEL ANTIFUNGAL 5,6-DIHYDRO-4-[(DIFLUOROETHYL)PHENYL]-4H-PYRROLO[1,2-a][1,4]BENZODIAZEPINE AND 4-(DIFLUOROETHYL)PHENYL-6H-PYRROLO[1,2-a][1,4]BENZODIAZEPINE DERIVATIVES

The present invention concerns novel compounds of Formula (I): wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.