1352429-51-6

Basic information

• Product Name: tert-butyl (R,R)-2-[N⁽¹⁾-benzylpiperidin-2-yl]-4-tert-butoxy-4-oxobutanoate
• Synonyms: tert-butyl (R,R)-2-[N⁽¹⁾-benzylpiperidin-2-yl]-4-tert-butoxy-4-oxobutanoate
• CAS NO: 1352429-51-6
• Molecular Weight: 403.562
• Mol File: 1352429-51-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (R,R)-2-[N⁽¹⁾-benzylpiperidin-2-yl]-4-tert-butoxy-4-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (R,R)-2-[N⁽¹⁾-benzylpiperidin-2-yl]-4-tert-butoxy-4-oxobutanoate(1352429-51-6)
• EPA Substance Registry System: tert-butyl (R,R)-2-[N⁽¹⁾-benzylpiperidin-2-yl]-4-tert-butoxy-4-oxobutanoate(1352429-51-6)

Safety Data

• Hazardous Substances Data: 1352429-51-6(Hazardous Substances Data)

Upstream product

• 14429-03-9 (R)-N-benzyl-N-(α-methyl-p-methoxybenzyl)amine 
• 100-52-7 benzaldehyde 
• 117471-84-8 1,1-dimethylethyl (E)-7-hydroxyhept-2-enoate 
• 27784-76-5 tert-butyl diethylphosphonoacetate 
• 1227062-94-3 tert-butyl (3R,αR)-3-[N-benzyl-N-(α-methyl-p-methoxybenzyl)amino]-7-iodoheptanoate 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 1227062-91-0 tert-butyl (R)-2-[N⁽¹⁾-benzylpiperidin-2-yl]acetate 
• 1227062-90-9 tert-butyl (R,R)-3-[N-benzyl-N-(α-methylbenzyl)amino]-7-iodoheptanoate 
• 1227062-89-6 tert-butyl (R,R)-3-[N-benzyl-N-(α-methylbenzyl)amino]-7-hydroxyheptanoate 

Relevant articles and documents

Asymmetric synthesis of piperidines and octahydroindolizines using a one-pot ring-closure/N-debenzylation procedure

The conjugate addition of an enantiopure lithium amide to a ζ-hydroxy-α,β-unsaturated ester followed by a one-pot ring-closure/N-debenzylation protocol has been used in the asymmetric syntheses of (S)-coniine and (R)-δ-coniceine (isolated as the corresponding hydrochloride salts), and (R,R)-1-(hydroxymethyl)octahydroindolizine (the bicyclic fragment of stellettamides A-C).