1353155-51-7

Basic information

• Product Name: [2-(2-methyl)-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy-N-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)]acetamide
• CAS NO: 1353155-51-7
• Molecular Weight: 784.053
• Mol File: 1353155-51-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [2-(2-methyl)-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy-N-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(2-methyl)-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy-N-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)]acetamide(1353155-51-7)
• EPA Substance Registry System: [2-(2-methyl)-3-(2-methylphenyl)-4(3H)-quinazolin-8-yloxy-N-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)]acetamide(1353155-51-7)

Safety Data

• Hazardous Substances Data: 1353155-51-7(Hazardous Substances Data)

Upstream product

• 24407-32-7 3,4,5,6-tetrabromophthalimide 
• 1319735-77-7 2-[3,4-dihydro-2-methyl-3-(2-methylphenyl)-4-oxoquinazolin-8-yloxy]acetic acid hydrazide 
• 5060-53-7 8-hydroxy-2-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone 
• 1319735-76-6 ethyl 2-[3,4-dihydro-2-methyl-3-(2-methylphenyl)-4-oxoquinazolin-8-yloxy]acetate 

Relevant articles and documents

Design, synthesis and anticonvulsant evaluation of novel 8-substituted-4(3H)-quinazolines

A new series of 8-substituted-4(3H)-quinazoline derivatives were synthesized, evaluated for their anticonvulsant activity against chemically (PTZ, picrotoxin and Strychnine) and electrically (MES) induced seizures and compared with the reference drugs valproate and methaqualone. Acid hydrazide, acetylhydrazine carboxylate and acetylhydrazinecarbodithioate were the most active compounds with relatively low neurotoxicity compared with the standard drugs. The obtained results proved that the mostly active compounds could be useful as a model for future design, adaptation and investigation to construct more active analogues. Springer Science+Business Media, LLC 2011.