137057-20-6

Basic information

• Product Name: Benzeneacetonitrile, a-(methoxymethyl)-a-[(trimethylsilyl)oxy]-
• CAS NO: 137057-20-6
• Molecular Formula: C13H19NO2Si
• Molecular Weight: 249.385
• Mol File: 137057-20-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzeneacetonitrile, a-(methoxymethyl)-a-[(trimethylsilyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetonitrile, a-(methoxymethyl)-a-[(trimethylsilyl)oxy]-(137057-20-6)
• EPA Substance Registry System: Benzeneacetonitrile, a-(methoxymethyl)-a-[(trimethylsilyl)oxy]-(137057-20-6)

Safety Data

• Hazardous Substances Data: 137057-20-6(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 4079-52-1 methoxymethyl phenyl ketone 

Downstream Products

• 137040-11-0 (RS)-1-azabicyclo<2.2.2>oct-3-yl (RS)-α-hydroxy-α-(methoxymethyl)-α-phenylacetate 
• 137040-04-1 ethyl α-hydroxy-α-(methoxymethyl)-α-phenylacetate 
• 137039-97-5 α-(methoxymethyl)-α-hydroxy-α-phenylacetic acid 
• 137039-90-8 2-Hydroxy-3-methoxy-2-phenyl-propionamide 

Relevant articles and documents

Synthesis and Muscarinic Cholinergic Receptor Affinities of 3-Quinuclidinyl α-(Alkoxyalkyl)-α-aryl-α-hydroxyacetates

Seven analogues of 3-quinuclidinyl benzilate (QNB) in which one phenyl ring was replaced by an alkoxyalkyl moiety were synthesized and their affinities for the muscarinic cholinergic receptor determined.An oxygen in the β-position of the moienty was not w

A convenient catalytic procedure for the addition of trimethylsilyl cyanide to functionalised ketones, mediated by InBr3 - Insight into the reaction mechanism

This paper describes a useful and practical methodology for the addition of trimethylsilyl cyanide (TMSCN) to a large variety of functionalised and unfunctionalised ketones in the presence of catalytic amounts of anhydrous InBr3. The optimum pr