13707-43-2

Basic information

• Product Name: Benzenesulfonamide, N-[(dimethylamino)methylene]-
• CAS NO: 13707-43-2
• Molecular Formula: C9H12N2O2S
• Molecular Weight: 212.272
• Mol File: 13707-43-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-[(dimethylamino)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-[(dimethylamino)methylene]-(13707-43-2)
• EPA Substance Registry System: Benzenesulfonamide, N-[(dimethylamino)methylene]-(13707-43-2)

Safety Data

• Hazardous Substances Data: 13707-43-2(Hazardous Substances Data)

Upstream product

• 55596-11-7 N-(2,2,2-trichloroethylidene)benzenesulfonamide 
• 124-40-3 dimethyl amine 
• 13909-34-7 N-benzylidenephenylsulfonamide 
• 23879-26-7 1-phenyl-4-dimethylamino-2-phenyl-1,3-diazabutadiene 
• 108228-47-3 1-p-tolyl-4-dimethylamino-2-phenyl-1,3-diazabutadiene 
• 473-29-0 N,N-Dichlorobenzenesulfonamide 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 98514-83-1 N-(pyridine-2-ylmethyl)benzenesulfonamide 
• 938-10-3 phenylsulfonyl azide 
• 10448-42-7 dimethyl-styryl-amine 
• 68-12-2 N,N-dimethyl-formamide 
• 98-09-9 benzenesulfonyl chloride 
• 2618-96-4 dibenzenesulfonamide 
• 103-83-3 N,N'-dimethylbenzylamine 

Relevant articles and documents

Preparation method of sulfonyl amidine with 2-Picolylamine and DMF-DMA as amine sources

The invention discloses a preparation method of sulfonyl amidine with 2-Picolylamine and DMF-DMA as amine sources. The method comprises the following steps: reacting sulfonyl chloride with 2-Picolylamine to obtain an intermediate product; and then reacting the intermediate product with DMF-DMA in the presence of a catalyst at a temperature of 60-100 DEG C, then performing cooling to room temperature, extracting the reaction solution with ethyl acetate, performing layering, drying and then concentrating to obtain a target product sulfonyl amidine. According to the method disclosed by the invention, the reaction of secondary sulfonamide and DMF-DMA is realized, and the synthesis path of sulfonyl amidine is expanded. The synthetic reaction is simple in operation, mild in condition and convenient in post-treatment, and the obtained intermediate product and the product are high in purity and yield.

A Novel Synthesis of N -Sulfonylformamidines from N Sulfonyl sulfonamides

N -Sulfonylformamidines were synthesized from N -sulfonylsulfonamides by reacting with p -toluenesulfonyl chloride (TsCl) and N, N - disubstituted formamides. In this reaction, it was expected that mixing TsCl with the N, N -disubstituted formamide would generate an iminium salt (Vilsmeier reagent). The reaction avoids the use of metal catalysts and hazardous reagents, and the desired N -sulfonylformamidines were obtained in 60% to quantitative yields.

Unexpected C=N bond formation via NaI-catalyzed oxidative de-tetra-hydrogenative cross-couplings between N,N-dimethyl aniline and sulfamides

A direct and convenient C=N bond formation reaction was reported, which was a de-tetra-hydrogenative cross-coupling (DTCC) reaction between N,N-dimethyl aniline and sulfamide under transition-metal-free conditions, and to give sulfonyl amidine derivatives in moderate to high yields.