10448-42-7

Basic information

• Product Name: Ethenamine, N,N-dimethyl-2-phenyl-
• CAS NO: 10448-42-7
• Molecular Formula: C10H13N
• Molecular Weight: 147.22
• Mol File: 10448-42-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethenamine, N,N-dimethyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethenamine, N,N-dimethyl-2-phenyl-(10448-42-7)
• EPA Substance Registry System: Ethenamine, N,N-dimethyl-2-phenyl-(10448-42-7)

Safety Data

• Hazardous Substances Data: 10448-42-7(Hazardous Substances Data)

Upstream product

• 124-40-3 dimethyl amine 
• 536-74-3 phenylacetylene 
• 18925-69-4 N,N-dimethyl-2-phenylacetamide 
• 127-19-5 N,N-dimethyl acetamide 
• 103-64-0 bromostyrene 
• 122-78-1 phenylacetaldehyde 

Downstream Products

• 117845-54-2 (E)-3-Dimethylamino-1-(2-nitro-phenyl)-2-phenyl-propenone 
• 13707-43-2 N,N-dimethyl-N′-(phenylsulfonyl)formimidamide 
• 29912-59-2 N,N-dimethyl-N′-(4-nitrophenylsulfonyl)formimidamide 
• 5684-60-6 2-Dimethylamino-1-methanesulfonyl-1-phenylethylene 
• 19244-68-9 3-Dimethylamino-4-phenyl-cyclobutan-1.2-dicarbonsaeure-diethylester 

Relevant articles and documents

Method for synthesizing enamine under catalysis of palladium imine complex containing pyridine ligands

The invention relates to a method for synthesizing enamine under catalysis of a palladium imine complex containing pyridine ligands. The method comprises steps as follows: phenylacetylene and secondary amine are taken as raw materials, the palladium imine

Transformation of Amides into Highly Functionalized Triazolines

Triazoles and triazolines are important classes of heterocyclic compounds known to exhibit biological activity. Significant focus has been given to the development of synthetic approaches for the preparation of triazoles, and they are today easily obtainable through a large variety of protocols. The number of synthetic procedures for the formation of triazolines, on the other hand, is limited and further research in this field is required. The protocol presented here gives access to a broad scope of 1,4,5-substituted 1,2,3-triazolines through a one-pot transformation of carboxamides. The two-step procedure involves a Mo(CO)6-catalyzed reduction of tertiary amides to afford the corresponding enamines, followed by in situ cycloaddition of organic azides to form triazolines. The amide reduction is chemoselective and allows for a wide variety of functional groups such as esters, ketones, aldehydes, and imines to be tolerated. Furthermore, a modification of this one-pot procedure gives access to the corresponding triazoles. The chemically stable amide functionality is demonstrated to be an efficient synthetic handle for the formation of highly substituted triazolines or triazoles.

Nickel catalyzed addition of -NH- containing compounds to vinyl and aryl halides

A process for producing unsaturated nitrogen containing compounds such as enamides, enamines and aryl amines/amides is disclosed. A vinyl halide or aryl halide is reacted with an -NH- containing compound in the presence of a catalytic amount of a catalyst precursor composition comprising zero-valent nickel and an organophosphine ligand. One step coupling of vinyl halides and aryl halides with -NH- containing compounds is made possible by practice of this invention.