1373152-63-6

Basic information

• Product Name: methyl 1-(4-methoxyphenyl)-6-oxo-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate
• Synonyms: methyl 1-(4-methoxyphenyl)-6-oxo-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate
• CAS NO: 1373152-63-6
• Molecular Weight: 441.464
• Mol File: 1373152-63-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 1-(4-methoxyphenyl)-6-oxo-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-(4-methoxyphenyl)-6-oxo-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate(1373152-63-6)
• EPA Substance Registry System: methyl 1-(4-methoxyphenyl)-6-oxo-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate(1373152-63-6)

Safety Data

• Hazardous Substances Data: 1373152-63-6(Hazardous Substances Data)

Upstream product

• 96013-53-5 1-(toluene-4-sulfonyl)-1,5-dihydropyrrol-2-one 
• 70736-27-5 C₉H₈N₂O₂ClCH₃O 

Relevant articles and documents

1,3-Dipolar cycloaddition of nitrile imines with α,β-unsaturated lactones, thiolactones and lactams: Synthesis of ring-fused pyrazoles

1,3-Dipolar cycloaddition of nitrile imines with α,β-unsaturated five- and six-membered lactones, thiolactones and lactams gave ring-fused pyrazoles. Regioisomeric mixtures have been obtained with the 5-substituted pyrazole as the major cycloadduct. Only with the five-membered lactone the major product was the 4-acyl derivative. Computational studies, the use of the topological analysis of the Fukui functions and the potential energy surfaces (PES) theory allowed a theoretical description of the local reactivity in agreement with the observed high regiochemistry and with the role of the heteroatom adjacent to the carbonyl group.