96013-53-5

Basic information

• Product Name: 1-(toluene-4-sulfonyl)-1,5-dihydropyrrol-2-one
• Synonyms: 1-(toluene-4-sulfonyl)-1,5-dihydropyrrol-2-one
• CAS NO: 96013-53-5
• Molecular Weight: 237.279
• Mol File: 96013-53-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(toluene-4-sulfonyl)-1,5-dihydropyrrol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(toluene-4-sulfonyl)-1,5-dihydropyrrol-2-one(96013-53-5)
• EPA Substance Registry System: 1-(toluene-4-sulfonyl)-1,5-dihydropyrrol-2-one(96013-53-5)

Safety Data

• Hazardous Substances Data: 96013-53-5(Hazardous Substances Data)

Upstream product

• 10019-95-1 N-tosylpyrrolidinone 
• 1252614-25-7 N-(p-toluenesulfonyl)-3-(phenylselanyl)-pyrrolidin-2-one 
• 847806-13-7 S-ethyl-S-ethenyl-N-(toluene-4-sulfonyl)sulfilimine 
• 127-65-1 chloroamine-T 
• 847806-04-6 3,3-dichloro-5-ethylthio-1-(toluene-4-sulfonyl)pyrrolidin-2-one 
• 847806-05-7 5-ethylthio-1-(toluene-4-sulfonyl)pyrrolidin-2-one 
• 17639-64-4 N-p-toluenesulfonylpyrrole 

Downstream Products

• 1373152-62-5 methyl 4-oxo-1-phenyl-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate 
• 1373152-41-0 methyl 6-oxo-1-phenyl-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate 
• 1373152-64-7 methyl 1-(4-methoxyphenyl)-4-oxo-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate 
• 1373152-63-6 methyl 1-(4-methoxyphenyl)-6-oxo-5-tosyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxylate 
• 96013-54-6 4-methyl-1-(toluene-4-sulfonyl)-pyrrolidin-2-one 
• 1514833-12-5 (R)-4-(dimethyl(phenyl)silyl)-1-tosyl-1,5-dihydro-2H-pyrrolidin-2-one 

Relevant articles and documents

Platinum-Catalyzed Desaturation of Lactams, Ketones, and Lactones

The development of a general platinum-catalyzed desaturation of N-protected lactams, ketones, and lactones to their conjugated α,β-unsaturated counterparts is reported. The reaction operates under mildly acidic conditions at room temperature or 50 °C. It is scalable and tolerates a wide range of functional groups. The complementary reactivity to the palladium-catalyzed desaturation is demonstrated in the efficient conversion of iodide, bromide, and sulfur-containing substrates.

Catalytic, asymmetric vinylogous Mukaiyama aldol reactions of pyrrole- and furan-based dienoxy silanes: How the diene heteroatom impacts stereocontrol

Denmark's chiral bisphosphoramide/silicon tetrachloride system performs as an excellent Lewis base-Lewis acid catalyst for the vinylogous Mukaiyama aldol reaction of pyrrole- and furan-based dienoxy silanes with aromatic and heteroaromatic aldehydes. This asymmetric methodology provides a powerful synthetic entry to a variety of d-hydroxylated g-butenolide-type frameworks with high efficiency and valuable margins of regio-, diastereo-, and enantioselectivity. Notably, the nature of the heteroatom within the vinylogous dienoxy silane donor heavily impacts the diastereocontrol, with syn-configured aldol adducts emerging from pyrroles bearing electron- withdrawing N-protecting groups (Boc, Ts, and Cbz) and anti-configured adducts prevailing when furan- or N-alkyl/alkenylpyrrole donors are involved.

A new synthesis of γ-lactams based on the reaction of vinyl sulfilimines with dichloroketene

(Chemical Equation Presented) The reactions of several aryl-, furanyl-, and vinyl substituted sulfilimines with dichloroketene proceeded at 25°C to yield thioalkyl substituted γ-lactams which, in turn, were converted to a variety of nitrogen-containing substrates.