137697-51-9

Basic information

• Product Name: Thiourea, N,N''-1,3-phenylenebis[N'-[2-(diethylamino)ethyl]-
• CAS NO: 137697-51-9
• Molecular Formula: C20H36N6S2
• Molecular Weight: 424.678
• Mol File: 137697-51-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thiourea, N,N''-1,3-phenylenebis[N'-[2-(diethylamino)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N,N''-1,3-phenylenebis[N'-[2-(diethylamino)ethyl]-(137697-51-9)
• EPA Substance Registry System: Thiourea, N,N''-1,3-phenylenebis[N'-[2-(diethylamino)ethyl]-(137697-51-9)

Safety Data

• Hazardous Substances Data: 137697-51-9(Hazardous Substances Data)

Upstream product

• 32813-52-8 2-diethylaminoethylisothiocyanate 
• 108-45-2 m-phenylenediamine 

Relevant articles and documents

Bis Basic Substituted Diaminobenzobisthiazoles as Potential Antiarthritic Agents

A series of benzobisthiazoles were screened for antiinflammatory activity in the carrageenan paw edema and adjuvant arthritis tests.Compound 26, 2,6-bis(N,N-diethylamino)benzobisthiazole, was found to inhibit the swelling of the uninjected paw in the prophylactic adjuvant arthritis model with an ED50 of 2.3 mg/kg orally.As with most compounds of this series, 26 was inactive in acute model of inflammation, such as paw edema: like steroids, it showed activity in the granuloma pouch assay but did not inhibit cyclooxygenase, indicating a mode of action different from the classical nonsteroidal antiinflammatory drugs (NSAID's).At doses higher than those producing antiinflammatory activity, 26 had some immunoregulating properties.