1382310-41-9

Basic information

• Product Name: 2-((4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)methylthio)-3-o-tolylquinazolin-4(3H)-one
• CAS NO: 1382310-41-9
• Molecular Weight: 484.579
• Mol File: 1382310-41-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-((4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)methylthio)-3-o-tolylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)methylthio)-3-o-tolylquinazolin-4(3H)-one(1382310-41-9)
• EPA Substance Registry System: 2-((4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)methylthio)-3-o-tolylquinazolin-4(3H)-one(1382310-41-9)

Safety Data

• Hazardous Substances Data: 1382310-41-9(Hazardous Substances Data)

Upstream product

• 37029-32-6 3,4-dihydro-3-(o-methylphenyl)-4-oxo-2-quinazolinylthioacetic acid hydrazide 
• 28831-36-9 ethyl 2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetate 
• 118-92-3 anthranilic acid 
• 95-53-4 o-toluidine 
• 37641-48-8 3-(o-methylphenyl)-2-thioquinazolin-4(3H)-one 
• 108-24-7 acetic anhydride 
• 56671-08-0 (4-oxo-3-o-tolyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetic acid (1-phenyl-ethylidene)-hydrazide 

Relevant articles and documents

Effect of temperature and solvents on ultrasonic velocity and thermodynamic parameters of 1,3,4-oxadiazole derivative solutions

The present work describes the synthesis, characterization, thermal analysis and physico-chemical parameters of 2-((4-acetyl-5-methyl-5-phenyl-4,5- dihydro-1,3,4-oxadiazol-2-yl)methylthio)-3-o-tolylquinazolin-4(3H)-one (PD I-H). The compound PDI-H is synthesized by using standard protocols; purity is monitored by using TLC and characterized by IR and NMR spectral techniques. The thermal behavior of PDI-H was studied by TGA and DTA techniques at a heating rate of 10 °C/min in nitrogen atmosphere. Thermal stability and kinetic parameters were determined according to the Freeman-Anderson method. The density (ρ), viscosity (η) and ultrasonic velocity (U) of pure solvents (chloroform (CF), N,N-dimethyl formamide (DMF)) and solutions of PDI-H (0.01-0.001 M) in CF and DMF were investigated at three different temperatures: 303 K, 308 K and 313 K. Using ρ, η and U data various thermodynamic parameters such as adiabatic compressibility (κa), intermolecular free path length (Lf), Rao's molar sound function (Rm), Van der Waals constant (b), internal pressure (π), free volume (Vf) and solvation number (S n) were calculated. The results obtained were interpreted in terms of solute-solvent and solute-solute interactions. The structure making or structure-breaking abilities of the solute in CF and DMF solvent were also studied.