1386972-47-9Relevant articles and documents
Solid-phase synthesis of 2-aminoethyl glucosamine sulfoforms
Liu, Runhui,Wei, Alexander
, p. 384 - 419 (2012/08/07)
Mono- and disaccharides of sulfonated glucosamines (GlcN sulfoforms) conjugated to 2-aminoethyl linkers were generated by solid-phase synthesis. Orthogonally protected intermediates were tethered onto tritylated polystyrene resin beads, subjected to amodular sequence of deprotection and sulfonation steps, then cleaved from solid support without degradation of N- or O-sulfate esters using solvolytic conditions, and finally purified by reverse-phase HPLC to afford the title compounds. Copyright Taylor & Francis Group, LLC.