139042-74-3

Basic information

• Product Name: Carbonic acid 1-(6-bromo-pyridin-2-yl)-2,2-dimethyl-propyl ester (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
• CAS NO: 139042-74-3
• Molecular Weight: 426.394
• Mol File: 139042-74-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbonic acid 1-(6-bromo-pyridin-2-yl)-2,2-dimethyl-propyl ester (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbonic acid 1-(6-bromo-pyridin-2-yl)-2,2-dimethyl-propyl ester (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester(139042-74-3)
• EPA Substance Registry System: Carbonic acid 1-(6-bromo-pyridin-2-yl)-2,2-dimethyl-propyl ester (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester(139042-74-3)

Safety Data

• Hazardous Substances Data: 139042-74-3(Hazardous Substances Data)

Upstream product

• 626-05-1 2,6-Dibromopyridine 
• 630-19-3 pivalaldehyde 
• 14602-86-9 (1R,2S,5R)-menthyl chloroformate 
• 127127-27-9 (rac)-1-(6-bromopyridin-2-yl)-2,2-dimethylpropan-1-ol 

Relevant articles and documents

Enantioselective Synthesis of Optically Active Pyridine Derivatives and C2-Symmetric 2,2'-Bipyridines

Optically active pyridine derivatives 2, 15, 18, 19, 21, 26, and 27 are obtained by enantioselective reduction of the corresponding ketones 5, 7, 11-13, 24, and 25 using the chiral borane reagent chlorodiisopinocampherylborane .Nickel(0)-mediated coupling of bromopyridines 2, 15, and 31 gives C2-symmetric 2,2'-bipyridines (R,R)-32, (R,R)-33, and (S,S)-38, respectively, which form metal complexex with Co(II), Pd(II), Cu(I), and Ag(I).Aryl-substituted pyridines 26, and 39-41 are synthesized by palladium(0)-catalized cross coupling of 2 and 15 with boronic acids 42-44.Key Words: 2,2-Bipyridines / Pyridines, optically active / Chiral ligands / Asymmetric Synthesis / Catalysis, enantioselective