1392150-08-1

Basic information

• Product Name: 5-[(3,5-difluorophenyl)thio]-1H-pyrazolo[3,4-b]pyrazin-3-amine
• Synonyms: 5-[(3,5-difluorophenyl)thio]-1H-pyrazolo[3,4-b]pyrazin-3-amine
• CAS NO: 1392150-08-1
• Molecular Weight: 279.273
• Mol File: 1392150-08-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-[(3,5-difluorophenyl)thio]-1H-pyrazolo[3,4-b]pyrazin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(3,5-difluorophenyl)thio]-1H-pyrazolo[3,4-b]pyrazin-3-amine(1392150-08-1)
• EPA Substance Registry System: 5-[(3,5-difluorophenyl)thio]-1H-pyrazolo[3,4-b]pyrazin-3-amine(1392150-08-1)

Safety Data

• Hazardous Substances Data: 1392150-08-1(Hazardous Substances Data)

Upstream product

• 766515-33-7 3-cyano-2-hydroxy-5-iodopyridine 
• 766515-34-8 2-chloro-5-iodopyridine-3-carbonitrile 
• 1392149-80-2 3-chloro-6-iodopyrazine-2-carbonitrile 
• 1392149-79-9 3-amino-6-iodopyrazine-2-carbonitrile 
• 1392149-78-8 N'-(3-cyano-5-iodopyrazine-2-yl)-N,N-dimethylformimidamide 
• 1244949-61-8 3-amino-6-iodopyrazine-2-carboxamide 
• 16298-03-6 Methyl 3-amino-2-pyrazinecarboxylate 
• 1458-16-8 methyl 3-amino-6-iodopyrazine-2-carboxylate 
• 99389-26-1 3,5-difluorobenzenethiol 
• 20577-27-9 2-hydroxy-3-cyanopyridine 

Downstream Products

• 1392151-76-6 1-(5-((3,5-difluorophenyl)thio)-1H-pyrazolo[3,4-b]pyridin-3-yl)-3-(4-(4-methylpiperazin-1-yl)phenyl)thiourea 
• 1392151-65-3 N-(5-(3,5-difluorophenylthio)-1-(4-(4-methylpiperazine-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido) benzoyl)-1H-pyrazolo[3,4-b]pyrazine-3-yl)-4-(4-methylpiperazine-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydro-2H-pyran-4-yl)acetamido)benzamide 
• 1392151-64-2 N-(5-((3,5-difluorophenyl)thio)-1H-pyrazolo[3,4-b]pyrazin-3-yl)-4-(4-methylpiperazin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)amino)benzamide 
• 1392151-89-1 5-(3,5-difluorophenyl sulfinyl)-1H-pyrazolo[3,4-b]pyrazin-3-amine 
• 1392151-92-6 5-[(3,5-difluorophenyl)sulfonyl]-1H-pyrazolo[3,4-b]pyrazin-3-amine 

Relevant articles and documents

DERIVATIVES OF AZAINDAZOLE OR DIAZAINDAZOLE TYPE FOR TREATING PAIN

The present invention relates to a compound of following formula (I): or a pharmaceutically acceptable salt or solvate of same, a tautomer of same, or a stereoisomer or mixture of stereoisomers of same in any proportions, such as a mixture of enantiomers, notably a racemic mixture; for use in the treatment of pain.

Derivatives of azaindoles or diazaindoles for treating pain

The present invention relates to a compound of following formula (I): or a pharmaceutically acceptable salt or solvate of same, a tautomer of same, or a stereoisomer or mixture of stereoisomers of same in any proportions, such as a mixture of enantiomers, notably a racemic mixture; for use in the treatment of pain.

DERIVATIVES OF AZAINDAZOLE OR DIAZAINDAZOLE TYPE AS MEDICAMENT

The present invention relates to a compound of following formula (I): or a pharmaceutically acceptable salt or solvate of same, a tautomer of same, or a stereoisomer or mixture of stereoisomers of same in any proportions, such as a mixture of enantiomers, notably a racemic mixture; as well as to the use of same as a drug, notably intended for the treatment of cancer, inflammation and neurodegenerative diseases such as Alzheimer's disease; to the use of same as a kinase inhibitor; to the pharmaceutical compositions comprising same; and to methods for the preparation of same.