1394820-98-4 Usage
Description
4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol is a quinoline derivative with the molecular formula C16H9FN2O4, featuring a fluoro and nitro group attached to a phenoxy ring. This chemical compound has a unique structure and properties that make it a promising candidate for various applications in pharmaceuticals and materials science. Its potential uses include the synthesis of organic compounds and possible pharmacological applications, although further research is required to fully explore its capabilities and effects.
Uses
Used in Pharmaceutical Industry:
4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol is used as a chemical intermediate for the synthesis of various organic compounds, particularly in the development of new pharmaceuticals. Its unique structure and properties may contribute to the discovery of novel drug candidates with potential therapeutic applications.
Used in Materials Science:
In the field of materials science, 4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol may be utilized in the development of advanced materials with specific properties. Its unique structure could potentially be incorporated into the design of new materials with applications in various industries, such as electronics, coatings, or sensors.
Used in Biological Research:
4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol may also be employed in biological research to investigate its potential pharmacological uses. Its unique structure and properties could provide insights into its biological activity, which may lead to the identification of new therapeutic targets or the development of novel drugs.
Note: The specific applications and reasons for using 4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol in different industries are not provided in the materials. The uses listed above are based on the general potential of the compound in pharmaceuticals, materials science, and biological research, considering its unique structure and properties. Further research and investigation are needed to fully understand its potential applications and effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1394820-98-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,4,8,2 and 0 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1394820-98:
(9*1)+(8*3)+(7*9)+(6*4)+(5*8)+(4*2)+(3*0)+(2*9)+(1*8)=194
194 % 10 = 4
So 1394820-98-4 is a valid CAS Registry Number.
1394820-98-4Relevant articles and documents
Discovery of N-substituted-3-phenyl-1,6-naphthyridinone derivatives bearing quinoline moiety as selective type II c-Met kinase inhibitors against VEGFR-2
Huang, Wei,She, Nengfang,Wang, Minshu,Wu, Fengxu,Xu, Hongchuang,Zhuo, Linsheng
, (2020)
New N-substituted-3-phenyl-1,6-naphthyridinone derivatives are designed and synthesized, based on structural modification of our previously reported compound 3. Extensive enzyme-based SAR studies and PK evaluation led to the discovery of compound 4r, with
Discovery of N-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors
Szabadkai, István,Torka, Robert,Garamv?lgyi, Rita,Baska, Ferenc,Gyulavári, Pál,Boros, Sándor,Illyés, Eszter,Choidas, Axel,Ullrich, Axel,órfi, László
, p. 6277 - 6292 (2018/07/05)
The overexpression of AXL kinase has been described in many types of cancer. Due to its role in proliferation, survival, migration, and resistance, AXL represents a promising target in the treatment of the disease. In this study we present a novel compound family that successfully targets the AXL kinase. Through optimization and detailed SAR studies we developed low nanomolar inhibitors, and after further biological characterization we identified a potent AXL kinase inhibitor with favorable pharmacokinetic profile. The antitumor activity was determined in xenograft models, and the lead compounds reduced the tumor size by 40% with no observed toxicity as well as lung metastasis formation by 66% when compared to vehicle control.
