139893-81-5 Usage
General Description
(1S,4S,5S)-4-bromo-6-oxabicyclo<3.2.1>octan-7-one is a chemical compound with the molecular formula C8H11BrO2. It is a cycloalkanone derivative that contains a bromine atom and a heterocyclic oxygen ring. (1S,4S,5S)-4-bromo-6-oxabicyclo<3.2.1>octan-7-one is a chiral molecule, meaning it has a non-superimposable mirror image, and is classified as a bicyclic compound due to its two interconnected ring structures. (1S,4S,5S)-4-bromo-6-oxabicyclo<3.2.1>octan-7-one may have applications in organic synthesis, medicinal chemistry, and material science due to its unique structural features and potential reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 139893-81-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,8,9 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 139893-81:
(8*1)+(7*3)+(6*9)+(5*8)+(4*9)+(3*3)+(2*8)+(1*1)=185
185 % 10 = 5
So 139893-81-5 is a valid CAS Registry Number.
139893-81-5Relevant articles and documents
Development of an Efficient Manufacturing Process for a Key Intermediate in the Synthesis of Edoxaban
Michida, Makoto,Ishikawa, Hideaki,Kaneda, Takeshi,Tatekabe, Shinya,Nakamura, Yoshitaka
, p. 524 - 534 (2019)
We report the development of a novel synthetic method to access a key intermediate in the synthesis of edoxaban. The main features of the new synthetic method are an improvement in the approach for the synthesis of a key chiral bromolactone, application of an interesting cyclization reaction utilizing neighboring group participation to construct a differentially protected 1,2-cis-diamine, and implementation of plug-flow reactor technology to enable the reaction of an unstable intermediate on multihundred kilogram scale. The overall yield for the preparation of edoxaban was significantly increased by implementing these changes and led to a more efficient and environmentally friendly manufacturing process.
