1401797-88-3

Basic information

• Product Name: N-(3-cyclopropylprop-2-yn-1-yl)-4-methylbenzenesulfonamide
• Synonyms: N-(3-cyclopropylprop-2-yn-1-yl)-4-methylbenzenesulfonamide
• CAS NO: 1401797-88-3
• Molecular Weight: 249.334
• Mol File: 1401797-88-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3-cyclopropylprop-2-yn-1-yl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-cyclopropylprop-2-yn-1-yl)-4-methylbenzenesulfonamide(1401797-88-3)
• EPA Substance Registry System: N-(3-cyclopropylprop-2-yn-1-yl)-4-methylbenzenesulfonamide(1401797-88-3)

Safety Data

• Hazardous Substances Data: 1401797-88-3(Hazardous Substances Data)

Upstream product

• 19451-11-7 cyclopropyliodide 
• 55022-46-3 4-methyl-N-prop-2-ynylbenzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 1428676-48-5 tert-butyl (3-cyclopropylprop-2-yn-1-yl)(tosyl)carbamate 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 101974-69-0 3-cyclopropylprop-2-yn-1-ol 

Downstream Products

• 1428676-21-4 (S)-8-cyclopropyl-5-[dimethyl(phenyl)silyl]-6-methyl-2-tosyl-1,2,3,4-tetrahydrocyclopenta[c]azepin-7(6H)-one 
• 1646499-60-6 (E )-N-(3-(4-methoxyphenyl)allyl)-4-methyl-N-(pent-2-ynyl)benzenesulfonamide 

Relevant articles and documents

Gold-Catalyzed Annulations of N-Propargyl Ynamides with Anthranils with Two Distinct Chemoselectivities

Gold-catalyzed annulation of N-propargyl ynamides with anthranils can proceed by two distinct mechanisms. In the case of a terminal N-propargyl ynamide, its resulting α-imino gold carbene reacts with a tethered alkyne to generate a vinyl cation to enable hydrolysis, which ultimately yields a pyrrolo[2,3-b]quinoline derivative after treatment with p-toluenesulfonic acid. For an internal alkyne, its α-imino gold carbene reacts with a tethered alkyne via either a vinyl cation or an alkenylgold carbene; both paths ultimately lead to a 4-ketone-2-aminopyrrole derivative. Our mechanistic analysis indicates that water is a better nucleophile than anthranil for terminal ynamides, whereas water and anthranils are equally reactive for internal ynamides.