1403036-53-2Relevant articles and documents
Synthesis and properties of DNA containing cyclonucleosides
Yueh, Han,Yu, Hongchuan,Theile, Christopher S.,Pal, Ayan,Horhota, Allen,Greco, Nicholas,Christianson, Carl V.,McLaughlin, Larry W.
, p. 661 - 679 (2012/11/07)
Here, we present efficient syntheses of the R and S diastereomers of 8,5′-cyclo-2′-deoxyadenosine and 6,5′-cyclo-2′- deoxyuridine. We incorporated these interesting nucleosides into DNA to study how the cyclo linkage affects the stability of duplex formation.