1403682-73-4

Basic information

• Product Name: 1-benzhydryl-1',4'-dimethyl-5',6',7',8'-tetrahydrospiro[azetidine-3,3'-isochromene]
• Synonyms: 1-benzhydryl-1',4'-dimethyl-5',6',7',8'-tetrahydrospiro[azetidine-3,3'-isochromene]
• CAS NO: 1403682-73-4
• Molecular Weight: 371.522
• Mol File: 1403682-73-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-benzhydryl-1',4'-dimethyl-5',6',7',8'-tetrahydrospiro[azetidine-3,3'-isochromene](CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzhydryl-1',4'-dimethyl-5',6',7',8'-tetrahydrospiro[azetidine-3,3'-isochromene](1403682-73-4)
• EPA Substance Registry System: 1-benzhydryl-1',4'-dimethyl-5',6',7',8'-tetrahydrospiro[azetidine-3,3'-isochromene](1403682-73-4)

Safety Data

• Hazardous Substances Data: 1403682-73-4(Hazardous Substances Data)

Upstream product

• 40320-60-3 N-benzhydryl 3-azetidinone 
• 4116-93-2 deca-2,8-diyne 

Relevant articles and documents

An expeditious route to eight-membered heterocycles by nickel-catalyzed cycloaddition: Low-temperature Csp2-Csp3 bond cleavage

A cool break: 3-Azetidinone and a variety of diynes undergo a cycloaddition reaction catalyzed by Ni/IPr to give dihydroazocine compounds (see scheme; IPr=1,3-bis(2,6-diisopropylphenyl)imidazolidene). The reaction involves a challenging CC bond cleavage step, yet, surprisingly, proceeds at low temperature.