140396-41-4Relevant articles and documents
Benzylation and nitrosation of 4-amino-2-(methylsulfanyl)pyrimidin-6(1H)-one (see abstract)
Glidewell, Christopher,Low, John N.,Marchal, Antonio,Quesada, Antonio
, p. o454-o460 (2003)
4-Amino-1-benzyl-2-(methylsulfanyl)pyrimidin-6(1H)-one, C 12H13N3OS, crystallizes in two polymorphic forms, both having space group P21/c, with Z′ = 1 for form (I) and Z′ = 2 for form (II). In (I), the molecules are linked by a single N-H...O hydrogen bond into simple C(6) chains, which are themselves linked into sheets by aromatic π-π interactions, while in (II), chains of edge-fused R42(8) and R44(24) rings are generated by four distinct N-H...O hydrogen bonds. In 4-amino-1-benzyl-2-(methylsulfanyl)-5-nitrosopyrimidin-6(1H)-one, C 12H12N4O2S, (III), where Z′ = 2, two independent three-centre N-H...(N,O) hydrogen bonds generate a C(5)C(6)[R12(5)] chain of rings. In 4-amino-6-benzyloxy-2-(methylsulfanyl)pyrimidine, C12H 13N3OS, (IV), which is isomeric with (I) and (II), a combination of N-H...N and N-H...O hydrogen bonds generates a sheet of alternating R22(8) and R66(28) rings.