140647-18-3

Basic information

• Product Name: 2-Propanol, 1-chloro-3-(4-methoxyphenoxy)-, acetate, (R)-
• CAS NO: 140647-18-3
• Molecular Formula: C12H15ClO4
• Molecular Weight: 258.702
• Mol File: 140647-18-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propanol, 1-chloro-3-(4-methoxyphenoxy)-, acetate, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanol, 1-chloro-3-(4-methoxyphenoxy)-, acetate, (R)-(140647-18-3)
• EPA Substance Registry System: 2-Propanol, 1-chloro-3-(4-methoxyphenoxy)-, acetate, (R)-(140647-18-3)

Safety Data

• Hazardous Substances Data: 140647-18-3(Hazardous Substances Data)

Upstream product

• 108-22-5 Isopropenyl acetate 
• 25772-85-4 (+/-)-1-chloro-3-(4-methoxyphenyloxy)-2-propanol 
• 142036-87-1 Acetic acid 1-chloromethyl-2-(4-methoxy-phenoxy)-ethyl ester 
• 108-05-4 vinyl acetate 

Relevant articles and documents

A facile and convenient chemoenzymatic synthesis of optically active O-(4-methoxyphenyl)-glycidol and 1,2-diacyl-sn-glycerol

A convenient preparation of the (R)- and (S)-enantiomers of O-(4-methoxyphenyl)-glycidol by a one-pot reduction of ketone 3 and in situ lipase mediated resolution is described. Activated moist aluminium oxide in the presence of Pseudomonas cepacia lipase immobilized on ceramic particles (PS-C) has been found effective for the transesterification leading to a high degree of enantioselectivity. These chiral glycidols were further used as a chiral precursor for the synthesis of biologically important 1,2-O-diacyl-sn-glycerol under mild reaction conditions. The present method is facile for the synthesis of chiral glycidols in high enantioselectivity when compared to the previously reported methods.