1408325-11-0

Basic information

• Product Name: C₂₇H₃₇N₃OS₃
• Synonyms: C₂₇H₃₇N₃OS₃
• CAS NO: 1408325-11-0
• Molecular Weight: 515.808
• Mol File: 1408325-11-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₇N₃OS₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₇N₃OS₃(1408325-11-0)
• EPA Substance Registry System: C₂₇H₃₇N₃OS₃(1408325-11-0)

Safety Data

• Hazardous Substances Data: 1408325-11-0(Hazardous Substances Data)

Upstream product

• 30062-49-8 2-amino-5-n-propyl-mercapto-1,3,4-thiadiazole 
• 162520-00-5 salirasib 

Relevant articles and documents

Synthesis and in vitro biological evaluation of farnesylthiosalicylic acid derivatives as anti-tumor carcinoma agents

Novel farnesylthiosalicylic acid (FTA) derivatives 5a-m with different substituted 1,3,4-thiadiazoles were synthesized. Compounds 5b, 5c, 5e and 5f displayed anti-tumor activities superior to FTA in most cancer cells tested. Furthermore, 5e induced tumor cell apoptosis, which was accompanied by lower Bcl-2 expression, but with higher Bax and caspase 3 expression activities in cancer cells.